| Literature DB >> 23993799 |
William Makis1, David Kurzencwyg, Marc Hickeson.
Abstract
The aim of this study was to examine whether positron emission tomography (PET)/computed tomography (CT) can detect more cases of colorectal cancer (CRC) than serum carcinoembryonic antigen (CEA), both at initial staging and during surveillance for recurrence. A retrospective review of 639 CRC patients imaged with PET/CT was performed. PET/CT was superior to serum CEA in detecting CRC, identifying 2.5 times as many CRC at initial staging compared to serum CEA and 1.5 times as many CRC recurrences. The current guideline recommendations of utilizing PET/CT only in the context of a rising serum CEA will miss more than one third of all CRC recurrences.Entities:
Keywords: CEA; Carcinoembryonic antigen; Colorectal cancer; FDG; PET/CT
Mesh:
Substances:
Year: 2013 PMID: 23993799 DOI: 10.1016/j.clinimag.2013.04.004
Source DB: PubMed Journal: Clin Imaging ISSN: 0899-7071 Impact factor: 1.605