Literature DB >> 23993799

18F-FDG PET/CT superior to serum CEA in detection of colorectal cancer and its recurrence.

William Makis1, David Kurzencwyg, Marc Hickeson.   

Abstract

The aim of this study was to examine whether positron emission tomography (PET)/computed tomography (CT) can detect more cases of colorectal cancer (CRC) than serum carcinoembryonic antigen (CEA), both at initial staging and during surveillance for recurrence. A retrospective review of 639 CRC patients imaged with PET/CT was performed. PET/CT was superior to serum CEA in detecting CRC, identifying 2.5 times as many CRC at initial staging compared to serum CEA and 1.5 times as many CRC recurrences. The current guideline recommendations of utilizing PET/CT only in the context of a rising serum CEA will miss more than one third of all CRC recurrences.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  CEA; Carcinoembryonic antigen; Colorectal cancer; FDG; PET/CT

Mesh:

Substances:

Year:  2013        PMID: 23993799     DOI: 10.1016/j.clinimag.2013.04.004

Source DB:  PubMed          Journal:  Clin Imaging        ISSN: 0899-7071            Impact factor:   1.605


  10 in total

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Journal:  Ann Surg Oncol       Date:  2022-10-11       Impact factor: 4.339

2.  Pre-operative TNM staging of primary colorectal cancer by (18)F-FDG PET-CT or PET: a meta-analysis including 2283 patients.

Authors:  Yanwei Ye; Tao Liu; Lisha Lu; Guojun Wang; Min Wang; Jingjing Li; Chao Han; Jianguo Wen
Journal:  Int J Clin Exp Med       Date:  2015-11-15

Review 3.  Future directions for the early detection of colorectal cancer recurrence.

Authors:  Avery S Walker; Eric K Johnson; Justin A Maykel; Alex Stojadinovic; Aviram Nissan; Bjorn Brucher; Bradley J Champagne; Scott R Steele
Journal:  J Cancer       Date:  2014-03-16       Impact factor: 4.207

4.  Association between carcinoembryonic antigen levels and the applied value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in post-operative recurrent and metastatic colorectal cancer.

Authors:  Wenzhe Bu; Ran Wei; Jinpeng Li; Lijun Wang; Congcong Shi; Jinlong Song; Shuangshuang Ma; Hua Chen; Ning Cong
Journal:  Oncol Lett       Date:  2014-09-11       Impact factor: 2.967

5.  Role of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Diagnosis of Newly Found Suspected Malignant Solitary Pulmonary Lesions in Patients Who Have Received Curative Treatment for Colorectal Cancer.

Authors:  Xiaozhou Yu; Xiuyu Song; Lei Zhu; Wei Chen; Dong Dai; Xiaofeng Li; Wengui Xu
Journal:  Gastroenterol Res Pract       Date:  2017-04-12       Impact factor: 2.260

6.  Diagnostic and prognostic value of preoperative 18F-fluorodeoxyglucose positron emission tomography/computed tomography for colorectal cancer: comparison with conventional computed tomography.

Authors:  Joo Young Lee; Soon Man Yoon; Jeong Tae Kim; Ki Bae Kim; Mi Jin Kim; Jae Geun Park; Taek-Gu Lee; Sang-Jeon Lee; Sung Soo Koong; Joung-Ho Han; Hee Bok Chae; Seon Mee Park; Sei Jin Youn
Journal:  Intest Res       Date:  2017-04-27

7.  Elevated tumor-to-liver uptake ratio (TLR) from 18F-FDG-PET/CT predicts poor prognosis in stage IIA colorectal cancer following curative resection.

Authors:  Jun Huang; Liang Huang; Jiaming Zhou; Yinghua Duan; Zhanwen Zhang; Xiaoyan Wang; Pinzhu Huang; Shuyun Tan; Ping Hu; Jianping Wang; Meijin Huang
Journal:  Eur J Nucl Med Mol Imaging       Date:  2017-08-15       Impact factor: 9.236

Review 8.  Blood CEA levels for detecting recurrent colorectal cancer.

Authors:  Brian D Nicholson; Bethany Shinkins; Indika Pathiraja; Nia W Roberts; Tim J James; Susan Mallett; Rafael Perera; John N Primrose; David Mant
Journal:  Cochrane Database Syst Rev       Date:  2015-12-10

9.  Diagnostic value of (18)F-FDG PET/CT as first choice in the detection of recurrent colorectal cancer due to rising CEA.

Authors:  Michael Gade; Magdalena Kubik; Rune V Fisker; Ole Thorlacius-Ussing; Lars J Petersen
Journal:  Cancer Imaging       Date:  2015-08-13       Impact factor: 3.909

10.  Clinical Etiology of Hypermetabolic Pelvic Lesions in Postoperative Positron Emission Tomography/Computed Tomography for Patients With Rectal and Sigmoid Cancer.

Authors:  Yun Hee Kang; Eunji Han; Geon Park
Journal:  Ann Coloproctol       Date:  2018-04-30
  10 in total

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