BACKGROUND AND OBJECTIVES: With the number of tattoos increasing, a rising number of complications have also been reported, such as allergic and foreign body reactions or the development of malignant tumors. We discuss 19 patients with alterations in skin tattoos, define clinicopathologic characteristics and give a brief review of the literature. PATIENTS AND METHODS: Biopsy specimens were obtained in 13 of 19 patients. In all cases, staining was performed with hematoxylin-eosin, periodic acid-Schiff, CD68, CD123, and CD163. The inflammatory infiltrate was classified according to the pattern analysis of Ackerman. RESULTS: Three of 19 patients (15.8%) had temporary tattoos with henna and 16 (84.2%) had permanent tattoos. Histologically, among the 13 biopsy specimens we found signs of acute contact dermatitis in 2 (15.3%), lupus-like patterns in 2 (15.3%), foreign body dermatitis in 5 (38.4%), deposition of pigment without inflammation or simple scarring in 2 (15.3%), and tumors in 2 patients (15.2%), 1 of which was a malignant melanoma. CONCLUSIONS: Clinical presentation frequently, but not always, correlates with the histologic pattern. Obtaining a biopsy can be helpful in determining further investigations, for example allergy testing or a search for systemic involvement in cases of tattoo sarcoidosis.
BACKGROUND AND OBJECTIVES: With the number of tattoos increasing, a rising number of complications have also been reported, such as allergic and foreign body reactions or the development of malignant tumors. We discuss 19 patients with alterations in skin tattoos, define clinicopathologic characteristics and give a brief review of the literature. PATIENTS AND METHODS: Biopsy specimens were obtained in 13 of 19 patients. In all cases, staining was performed with hematoxylin-eosin, periodic acid-Schiff, CD68, CD123, and CD163. The inflammatory infiltrate was classified according to the pattern analysis of Ackerman. RESULTS: Three of 19 patients (15.8%) had temporary tattoos with henna and 16 (84.2%) had permanent tattoos. Histologically, among the 13 biopsy specimens we found signs of acute contact dermatitis in 2 (15.3%), lupus-like patterns in 2 (15.3%), foreign body dermatitis in 5 (38.4%), deposition of pigment without inflammation or simple scarring in 2 (15.3%), and tumors in 2 patients (15.2%), 1 of which was a malignant melanoma. CONCLUSIONS: Clinical presentation frequently, but not always, correlates with the histologic pattern. Obtaining a biopsy can be helpful in determining further investigations, for example allergy testing or a search for systemic involvement in cases of tattoo sarcoidosis.
Authors: Parvez S Islam; Christopher Chang; Carlo Selmi; Elena Generali; Arthur Huntley; Suzanne S Teuber; M Eric Gershwin Journal: Clin Rev Allergy Immunol Date: 2016-04 Impact factor: 8.667
Authors: F Breier; D Loader; G Wasilewicz; W Brenner; P Sator; R Feldmann; A Stella; W Osterode; G Falkenberg; A Steiner; W Jurecka Journal: Hautarzt Date: 2016-01 Impact factor: 0.751
Authors: Marike Leijs; Hannah Schaefer; Albert Rübben; Claudio Cacchi; Thomas Rustemeyer; Sebastiaan van der Bent Journal: Curr Oncol Date: 2021-11-15 Impact factor: 3.677