BACKGROUND: There are many studies of the association between early-onset androgenetic alopecia (AGA) and metabolic syndrome (MS), which is known to increase the risk of cardiovascular diseases. However the results are inconsistent. There is no study in a Thai population. OBJECTIVE: To evaluate the association of early-onset AGA and metabolic syndrome in Thai male patients. MATERIAL AND METHOD: Patients were recruited from the check-up clinic. There were 80 male subjects: 40 with a diagnosis of early-onset AGA (before 35 years of age) and 40 control subjects without alopecia. Data from medical records, self-administered forms, and interview were collected and analyzed. RESULTS: Patients with early-onset AGA had the 3.48-fold higher risk of metabolic syndrome than in a control group (p = 0.015, odd ratio = 3.48, 95% confidence interval = 1.25-9.75). There was no relationship between AGA severity and metabolic syndrome (p = 0.629). There were no significant differences between the groups in terms of metabolic syndrome parameter CONCLUSION: The present study found the association between early onset A GA and metabolic syndrome in Thai men. Early detection of metabolic syndrome in this population may be useful to prevent cardiovascular diseases.
BACKGROUND: There are many studies of the association between early-onset androgenetic alopecia (AGA) and metabolic syndrome (MS), which is known to increase the risk of cardiovascular diseases. However the results are inconsistent. There is no study in a Thai population. OBJECTIVE: To evaluate the association of early-onset AGA and metabolic syndrome in Thai male patients. MATERIAL AND METHOD:Patients were recruited from the check-up clinic. There were 80 male subjects: 40 with a diagnosis of early-onset AGA (before 35 years of age) and 40 control subjects without alopecia. Data from medical records, self-administered forms, and interview were collected and analyzed. RESULTS:Patients with early-onset AGA had the 3.48-fold higher risk of metabolic syndrome than in a control group (p = 0.015, odd ratio = 3.48, 95% confidence interval = 1.25-9.75). There was no relationship between AGA severity and metabolic syndrome (p = 0.629). There were no significant differences between the groups in terms of metabolic syndrome parameter CONCLUSION: The present study found the association between early onset A GA and metabolic syndrome in Thai men. Early detection of metabolic syndrome in this population may be useful to prevent cardiovascular diseases.
Authors: Mukunda Ranga Swaroop; B Manohara Kumar; B D Sathyanarayana; D Yogesh; J C Raghavendra; Priyanka Kumari Journal: Indian J Dermatol Date: 2019 Jan-Feb Impact factor: 1.494
Authors: Rossella Cannarella; Rosita A Condorelli; Federica Dall'Oglio; Sandro La Vignera; Laura M Mongioì; Giuseppe Micali; Aldo E Calogero Journal: Int J Endocrinol Date: 2020-02-12 Impact factor: 3.257