Aye Aung1, Shukri Alqudihy1, Lisa Rybicki1, Alexandra Platt1, Mellar P Davis2. 1. Palliative Medicine and Supportive Oncology Services, Taussig Cancer Institute, Cleveland, OH, USA. 2. Palliative Medicine and Supportive Oncology Services, Taussig Cancer Institute, Cleveland, OH, USA Cleveland Clinic Lerner School of Medicine, Case Western Reserve University, Cleveland, OH, USA Cleveland Clinic Palliative Medicine Clinical Fellowship Program, Cleveland clinic, Cleveland, OH, USA davism6@ccf.org.
Abstract
INTRODUCTION: Low creatinine and albumin are found among the chronically ill patients. This study retrospectively reviewed albumin and creatinine levels for survival in patients upon admission. METHODS: Records of patients admitted over 2 months were reviewed. Recursive partitioning analysis (RPA) identified cutpoints in albumin and creatinine that predicted survival. Kaplan-Meier survival, Cox proportional hazards, and stepwise Cox analyses identified prognostic factors. RESULTS: Of 83 patients, 81 were assessable. Variables for worse survival were albumin <3.1 g/dL, creatinine >0.93 mg/dL, and male gender. Albumin by continuous, median, RPA, and tertiles was significant; creatinine by RPA. Hazard ratio for albumin >3.1 was 0.28 (P < .001) and for creatinine >0.91 mg/dL was 1.8 (P = .046). DISCUSSION AND CONCLUSION: Albumin and creatinine are prognostically important.
INTRODUCTION: Low creatinine and albumin are found among the chronically ill patients. This study retrospectively reviewed albumin and creatinine levels for survival in patients upon admission. METHODS: Records of patients admitted over 2 months were reviewed. Recursive partitioning analysis (RPA) identified cutpoints in albumin and creatinine that predicted survival. Kaplan-Meier survival, Cox proportional hazards, and stepwise Cox analyses identified prognostic factors. RESULTS: Of 83 patients, 81 were assessable. Variables for worse survival were albumin <3.1 g/dL, creatinine >0.93 mg/dL, and male gender. Albumin by continuous, median, RPA, and tertiles was significant; creatinine by RPA. Hazard ratio for albumin >3.1 was 0.28 (P < .001) and for creatinine >0.91 mg/dL was 1.8 (P = .046). DISCUSSION AND CONCLUSION:Albumin and creatinine are prognostically important.
Authors: Jae Min Lee; Sang Hyub Lee; Kwang Hyun Chung; Jin Myung Park; Ban Seok Lee; Woo Hyun Paik; Joo Kyung Park; Ji Kon Ryu; Yong-Tae Kim Journal: World J Gastroenterol Date: 2015-06-28 Impact factor: 5.742
Authors: Lea Kum; Alexander Friedrich; Markus Kieler; Elias Meyer; Petar Popov; Paul Kössler; Anna Kitta; Feroniki Adamidis; Raimund Oberle; Eva Katharina Masel; Matthias Unseld Journal: Nutrients Date: 2022-02-11 Impact factor: 5.717