Literature DB >> 23990573

Cytokine and chemokine levels in patients infected with the novel avian influenza A (H7N9) virus in China.

Ying Chi1, Yefei Zhu, Tian Wen, Lunbiao Cui, Yiyue Ge, Yongjun Jiao, Tao Wu, Aihua Ge, Hong Ji, Ke Xu, Changjun Bao, Zheng Zhu, Xian Qi, Bin Wu, Zhiyang Shi, Fenyang Tang, Zheng Xing, Minghao Zhou.   

Abstract

H7N9 avian influenza is an emerging viral disease in China caused by avian influenza A (H7N9) virus. We investigated host cytokine and chemokine profiles in serum samples of H7N9 patients by multiplex-microbead immunoassays. Statistical analysis showed that IP-10, IL-6, IL-17, and IL-2 were increased in H7N9 infected patients. Furthermore, IL-6 and the chemokine IP-10 were significantly higher in severe H7N9 patients compared to nonsevere H7N9 cases. We suggest that proinflammatory cytokine responses, characterized by a combined Th1/Th17 cytokine induction, are partially responsible for the disease progression of patients with H7N9 infection.

Entities:  

Keywords:  H7N9 avian influenza; chemokine; cytokine

Mesh：

Substances：

Year:  2013        PMID： 23990573     DOI： 10.1093/infdis/jit440

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  47 in total

Review 1.  Re-understanding anti-influenza strategy: attach equal importance to antiviral and anti-inflammatory therapies.

Authors:  Zhengtu Li; Li Li; Shuai Zhao; Jing Li; Hongxia Zhou; Yunhui Zhang; Zifeng Yang; Bing Yuan
Journal:  J Thorac Dis       Date:  2018-07       Impact factor: 2.895

2.  Avian influenza A (H7N9) virus infections in humans across five epidemics in mainland China, 2013-2017.

Authors:  David S C Hui; Nelson Lee; Paul K S Chan
Journal:  J Thorac Dis       Date:  2017-12       Impact factor: 2.895

3.  1918 H1N1 Influenza Virus Replicates and Induces Proinflammatory Cytokine Responses in Extrarespiratory Tissues of Ferrets.

Authors:  Emmie de Wit; Jurre Y Siegers; Jacqueline M Cronin; Sarah Weatherman; Judith M van den Brand; Lonneke M Leijten; Peter van Run; Lineke Begeman; Henk-Jan van den Ham; Arno C Andeweg; Trenton Bushmaker; Dana P Scott; Greg Saturday; Vincent J Munster; Heinz Feldmann; Debby van Riel
Journal:  J Infect Dis       Date:  2018-03-28       Impact factor: 5.226

4.  Hygrothermal environment may cause influenza pandemics through immune suppression.

Authors:  Xian-Lin Wu; Yu-Hong Luo; Jia Chen; Bin Yu; Kang-Li Liu; Jin-Xiong He; Su-Hong Lu; Jie-Xing Li; Sha Wu; Zhen-You Jiang; Xiao-Yin Chen
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

5.  Plasma Cytokines and Chemokines in Zambian Children With Measles: Innate Responses and Association With HIV-1 Coinfection and In-Hospital Mortality.

Authors:  Wen-Hsuan W Lin; Ashley N Nelson; Judith J Ryon; William J Moss; Diane E Griffin
Journal:  J Infect Dis       Date:  2017-03-01       Impact factor: 5.226

6.  A(H7N9) virus results in early induction of proinflammatory cytokine responses in both human lung epithelial and endothelial cells and shows increased human adaptation compared with avian H5N1 virus.

Authors:  Hui Zeng; Jessica A Belser; Cynthia S Goldsmith; Kortney M Gustin; Vic Veguilla; Jacqueline M Katz; Terrence M Tumpey
Journal:  J Virol       Date:  2015-02-11       Impact factor: 5.103

7.  Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge.

Authors:  M T McClain; R Henao; J Williams; B Nicholson; T Veldman; L Hudson; E L Tsalik; R Lambkin-Williams; A Gilbert; A Mann; G S Ginsburg; C W Woods
Journal:  Clin Exp Immunol       Date:  2015-12-16       Impact factor: 4.330

Review 8.  Avian influenza A (H7N9) virus: from low pathogenic to highly pathogenic.

Authors:  William J Liu; Haixia Xiao; Lianpan Dai; Di Liu; Jianjun Chen; Xiaopeng Qi; Yuhai Bi; Yi Shi; George F Gao; Yingxia Liu
Journal:  Front Med       Date:  2021-04-16       Impact factor: 4.592

Review 9.  CC and CXC chemokines play key roles in the development of polyomaviruses related pathological conditions.

Authors:  Mohammad Hassan Mohammadi; Ashraf Kariminik
Journal:  Virol J       Date:  2021-06-03       Impact factor: 4.099

10.  Comprehensive Immunologic Evaluation of Bronchoalveolar Lavage Samples from Human Patients with Moderate and Severe Seasonal Influenza and Severe COVID-19.

Authors:  Daniel Reynolds; Cristina Vazquez Guillamet; Aaron Day; Nicholas Borcherding; Rodrigo Vazquez Guillamet; José Alberto Choreño-Parra; Stacey L House; Jane A O'Halloran; Joaquín Zúñiga; Ali H Ellebedy; Derek E Byers; Philip A Mudd
Journal:  J Immunol       Date:  2021-08-04       Impact factor: 5.426
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.