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Literature DB >> 23989266

Heptachlor induced changes in fenitrothion metabolism.

Abstract

Pretreatment of rats with heptachlor administered in the food for 3 months increases the metabolism of fenitrothion. Comparison of oxon analogue levels in the blood and livers of pretreated and control animals suggests that the conversion of fenitrothion to its oxon analogue is enhanced and accelerated. This was studied by tracer methods, using P-fenitrothion.

Entities: Chemical Species

Year: 1970 PMID： 23989266 DOI： 10.1007/BF01558309

Source DB: PubMed Journal: Bull Environ Contam Toxicol ISSN： 0007-4861 Impact factor: 2.151

21 in total

1. MORPHOLOGICAL CHANGES IN THE LIVER ACCOMPANYING STIMULATION OF MICROSOMAL DRUG METABOLIZING ENZYME ACTIVITY BY PHENOBARBITAL, CHLORDANE, BENZPYRENE OR METHYL-CHOLANTHRENE IN RATS.

Authors: J R FOUTS; L A ROGERS
Journal: J Pharmacol Exp Ther Date: 1965-01 Impact factor: 4.030

2. FURTHER STUDIES ON THE STIMULATION OF HEPATIC MICROSOMAL DRUG METABOLIZING ENZYMES BY DDT AND ITS ANALOGS.

Authors: L G HART; J R FOUTS
Journal: Naunyn Schmiedebergs Arch Exp Pathol Pharmakol Date: 1965-01-08

3. Stimulatory effects of chlordane on hepatic microsomal drug metabolism in the rat.

Authors: L G HART; R W SHULTICE; J R FOUTS
Journal: Toxicol Appl Pharmacol Date: 1963-05 Impact factor: 4.219

4. [Enzyme induction and increase of endoplasmic reticulum in liver cells during phenobarbital (Luminal) therapy].

Authors: H REMMER; H J MERKER
Journal: Klin Wochenschr Date: 1963-03-15

5. Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs.

Authors: A H CONNEY; C DAVISON; R GASTEL; J J BURNS
Journal: J Pharmacol Exp Ther Date: 1960-09 Impact factor: 4.030

6. Stimulation by chlordane of hepatic drug metabolism in the squirrel monkey.

Authors: R L Cram; M R Juchau; J R Fouts
Journal: J Lab Clin Med Date: 1965-12

7. [Stimulation of several microsomal drug oxidations by phenobarbital, methylcholanthrene and chlorophenothane, single and in combinations].

Authors: H Uehleke
Journal: Naunyn Schmiedebergs Arch Exp Pathol Pharmakol Date: 1967

Heptachlor induced changes in fenitrothion metabolism.

1. MORPHOLOGICAL CHANGES IN THE LIVER ACCOMPANYING STIMULATION OF MICROSOMAL DRUG METABOLIZING ENZYME ACTIVITY BY PHENOBARBITAL, CHLORDANE, BENZPYRENE OR METHYL-CHOLANTHRENE IN RATS.

2. FURTHER STUDIES ON THE STIMULATION OF HEPATIC MICROSOMAL DRUG METABOLIZING ENZYMES BY DDT AND ITS ANALOGS.

3. Stimulatory effects of chlordane on hepatic microsomal drug metabolism in the rat.

4. [Enzyme induction and increase of endoplasmic reticulum in liver cells during phenobarbital (Luminal) therapy].

5. Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs.

6. Stimulation by chlordane of hepatic drug metabolism in the squirrel monkey.

7. [Stimulation of several microsomal drug oxidations by phenobarbital, methylcholanthrene and chlorophenothane, single and in combinations].

8. [Toxicological characteristics of small repeated doses of the insecticide heptachlorine].

9. Effects of pesticides on drug and steroid metabolism.

10. Activation of some organophosphorus insecticides by liver microsomes from phenobarbital-treated mice.

1. [Metabolism of pesticides resulting from combined administration].