OBJECTIVE: To estimate the prevalence of maternal colonizers in South Asia and their potential to colonize the umbilicus, an important precondition causing neonatal sepsis. STUDY DESIGN: We conducted a cross-sectional study at a maternity center in Dhaka with 1219 pregnant women and a subset of 152 newborns from 15 January to 31 October 2011. During labor, study paramedics collected vaginal swabs for bacterial culture and rectal swabs for Group B Streptococcus (GBS) testing. Community health workers collected neonatal umbilical swabs. Log-binomial regression models were used to estimate risk ratios. RESULT: In all, 454 women (37.2%, 95% confidence interval (CI) 34.5 to 40.0%) were colonized. The most common organisms isolated were Staphylococcus aureus, Non-GBS and GBS. A total of 94 women (7.7%, 95% CI 6.2 to 9.2%) were colonized with GBS. The risk of GBS umbilical colonization was higher (RR=12.98, 95% CI 3.97 to 42.64) among newborns of mothers with GBS colonization. CONCLUSION: Newborns of mothers colonized with GBS are at higher risk of developing umbilical colonization.
OBJECTIVE: To estimate the prevalence of maternal colonizers in South Asia and their potential to colonize the umbilicus, an important precondition causing neonatal sepsis. STUDY DESIGN: We conducted a cross-sectional study at a maternity center in Dhaka with 1219 pregnant women and a subset of 152 newborns from 15 January to 31 October 2011. During labor, study paramedics collected vaginal swabs for bacterial culture and rectal swabs for Group B Streptococcus (GBS) testing. Community health workers collected neonatal umbilical swabs. Log-binomial regression models were used to estimate risk ratios. RESULT: In all, 454 women (37.2%, 95% confidence interval (CI) 34.5 to 40.0%) were colonized. The most common organisms isolated were Staphylococcus aureus, Non-GBS and GBS. A total of 94 women (7.7%, 95% CI 6.2 to 9.2%) were colonized with GBS. The risk of GBS umbilical colonization was higher (RR=12.98, 95% CI 3.97 to 42.64) among newborns of mothers with GBS colonization. CONCLUSION: Newborns of mothers colonized with GBS are at higher risk of developing umbilical colonization.
Authors: Samir K Saha; Zabed B Ahmed; Joyanta K Modak; Hakka Naziat; Shampa Saha; Mohammad A Uddin; Maksuda Islam; Abdullah H Baqui; Gary L Darmstadt; Stephanie J Schrag Journal: J Clin Microbiol Date: 2017-05-17 Impact factor: 5.948
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Authors: Joseph Ngonzi; Lisa M Bebell; Joel Bazira; Yarine Fajardo; Dan Nyehangane; Yap Boum; Deborah Nanjebe; Adeline Boatin; Jerome Kabakyenga; Yves Jacquemyn; Jean-Pierre Van Geertruyden; Laura E Riley Journal: Int J Microbiol Date: 2018-09-20
Authors: Nguyen Thanh Viet; Vu Van Du; Nghiem Duc Thuan; Hoang Van Tong; Nguyen Linh Toan; Can Van Mao; Nguyen Van Tuan; Srinivas Reddy Pallerla; Dennis Nurjadi; Thirumalaisamy P Velavan; Ho Anh Son Journal: Antibiotics (Basel) Date: 2021-05-13