| Literature DB >> 23988135 |
Cynthia Ortinau1, Dimitrios Alexopoulos, Donna Dierker, David Van Essen, John Beca, Terrie Inder.
Abstract
Infants with congenital heart disease have altered brain development. We characterized cortical folding, a critical part of brain development, in congenital heart disease infants and demonstrated an overall decrease in cortical surface area and cortical folding with regional alterations in the right lateral sulcus and left orbitofrontal region, cingulate region, and central sulcus. These abnormalities were present prior to surgery.Entities:
Keywords: CHD; CSA; Congenital heart disease; Cortical surface area; GI; Gyrification index; MRI; Magnetic resonance imaging
Mesh:
Year: 2013 PMID: 23988135 PMCID: PMC3905308 DOI: 10.1016/j.jpeds.2013.06.045
Source DB: PubMed Journal: J Pediatr ISSN: 0022-3476 Impact factor: 4.406