Literature DB >> 23987521

Comprehensive analysis of sexual function outcome in prostate cancer patients after robot-assisted radical prostatectomy.

Seung Hyo Woo1, Dong Il Kang, Yun-Sok Ha, Amirali Hassanzadeh Salmasi, Jeong Hyun Kim, Dong-Hyeon Lee, Wun-Jae Kim, Isaac Yi Kim.   

Abstract

PURPOSE: The recovery of potency following radical prostatectomy is complex and has a very wide range. In this study, we analyzed in detail the precise pattern of recovery of potency following robot-assisted radical prostatectomy (RARP).
MATERIALS AND METHODS: Prospectively collected database of patients with a minimum follow-up of 1 year after RARP were evaluated retrospectively. Of 503 patients identified, 483 patients completed the sexual health inventory for men (SHIM) preoperatively and postoperatively every 3 months for the first 12 months. Overall potency, usage of phosphodiesterase type-5 (PDE-5) inhibitors, and return to baseline erectile function were evaluated. Potency was defined as having erection that is sufficient for sexual intercourse more than 50% of attempts, while quality potency was defined as being potent without the use of PDE-5 inhibitors.
RESULTS: Preoperatively, the overall potency and quality potency rate were 67.1% and 48.1%, respectively. Postoperatively, the overall potency rate was 61.4%, while the quality potency rate was 37.2%. In multivariate regression analysis, independent predictors of potency recovery were young age (<60), preoperative potency status, and bilateral preservation of neurovascular bundles (NVBs). In men with SHIM>21, the overall potency and quality potency rate were 79.7% and 41.2%, respectively. More importantly, only 21.4% of the men with normal erection preoperatively (SHIM>21) returned to baseline erectile function (SHIM>21) 12 months after surgery.
CONCLUSIONS: This study indicates that young age (<60), preoperative potency, and bilateral preservation of NVBs were positive predictors of potency recovery following RARP. However, an overwhelming majority of men experience a deterioration in the overall quality of erection after RARP.

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Year:  2013        PMID: 23987521     DOI: 10.1089/end.2013.0304

Source DB:  PubMed          Journal:  J Endourol        ISSN: 0892-7790            Impact factor:   2.942


  6 in total

1.  Factors predicting outcomes of penile rehabilitation with udenafil 50 mg following radical prostatectomy.

Authors:  T-H Kim; Y-S Ha; S H Choi; E S Yoo; B W Kim; S-J Yun; W-J Kim; Y S Kwon; T G Kwon
Journal:  Int J Impot Res       Date:  2015-10-29       Impact factor: 2.896

2.  Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years.

Authors:  Daniel A Barocas; JoAnn Alvarez; Matthew J Resnick; Tatsuki Koyama; Karen E Hoffman; Mark D Tyson; Ralph Conwill; Dan McCollum; Matthew R Cooperberg; Michael Goodman; Sheldon Greenfield; Ann S Hamilton; Mia Hashibe; Sherrie H Kaplan; Lisa E Paddock; Antoinette M Stroup; Xiao-Cheng Wu; David F Penson
Journal:  JAMA       Date:  2017-03-21       Impact factor: 56.272

Review 3.  Erection rehabilitation following prostatectomy--current strategies and future directions.

Authors:  Nikolai A Sopko; Arthur L Burnett
Journal:  Nat Rev Urol       Date:  2016-03-15       Impact factor: 14.432

4.  Flexibility in Men's Sexual Practices in Response to Iatrogenic Erectile Dysfunction after Prostate Cancer Treatment.

Authors:  Gary W Dowsett; Anthony Lyons; Duane Duncan; Richard J Wassersug
Journal:  Sex Med       Date:  2014-08       Impact factor: 2.491

Review 5.  The controversy surrounding penile rehabilitation after radical prostatectomy.

Authors:  Jonathan Clavell-Hernández; Run Wang
Journal:  Transl Androl Urol       Date:  2017-02

6.  Predicting trajectories of recovery in prostate cancer patients undergone Robot-Assisted Radical Prostatectomy (RARP).

Authors:  Chiara Marzorati; Dario Monzani; Ketti Mazzocco; Francesca Pavan; Gabriele Cozzi; Ottavio De Cobelli; Massimo Monturano; Gabriella Pravettoni
Journal:  PLoS One       Date:  2019-04-04       Impact factor: 3.240

  6 in total

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