| Literature DB >> 23987429 |
Tao Qiu1, Xiaojing Ma, Ming Ye, Ruyue Yuan, Yanna Wu.
Abstract
The extracellular polysaccharide (LEP) produced by Lachnum YM281 was obtained from the fermentation broth, and LEP-1b with molecular weight of 4.02×10(4) Da was separated and sequentially purified through DEAE-cellulose 52 column chromatography and Sepharose CL-6B column chromatography. GC-MS, IR and NMR ((1)H, (13)C) spectroscopy analysis indicated that the repeat unit of LEP-1b was: [formula; see text] The effects of LEP-1b on the serum lipids, liver lipids levels and aminotransferase activities of model mice with hyperlipidemic fatty live were studied, and the results showed that LEP-1b had strong lipid lowering and liver protecting effects on mice with hyperlipidemic fatty live.Entities:
Keywords: Extracellular polysaccharide; Lachnum YM281; Lipid lowering; Liver protecting; Structure
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Year: 2013 PMID： 23987429 DOI： 10.1016/j.carbpol.2013.07.014
Source DB: PubMed Journal: Carbohydr Polym ISSN： 0144-8617 Impact factor: 9.381