Literature DB >> 23987150

Results of a national population-based study of outcomes of surgery for renal tumors associated with inferior vena cava thrombus.

Paul Toren1, Robert Abouassaly, Narhari Timilshina, Girish Kulkarni, Shabbir Alibhai, Antonio Finelli.   

Abstract

OBJECTIVE: To determine whether surgeon or hospital volume effects in-hospital mortality or complications of radical nephrectomy with concomitant removal of inferior vena cava (IVC) thrombus, we examine a national population-based cohort. Radical nephrectomy with removal of IVC thrombus is a complex urologic operation, which, similar to other major surgical procedures, may have an association between provider volume and outcomes.
METHODS: Canadian Institute for Health Information administrative codes were used to identify nephrectomies associated with IVC manipulation in Canada from 1998 to 2007. Canadian Institute for Health Information databases yielded information on in-hospital mortality and complications for the hospital admission at surgery. Multivariate regression analysis was performed to assess the effect of surgeon and hospital volume on in-hospital mortality and complications, adjusting for age, sex, comorbidity, year of surgery, and region.
RESULTS: During the study period, 816 radical nephrectomies with associated IVC thrombectomy were performed on 521 men and 295 women. The in-hospital mortality rate was 7%. Notably, 75% of deaths occurred in the first 2 cases of surgeon experience. Median length of stay was 10 days. Complications were noted in 633 patients (78%). Fifty-eight patients with concomitant cardiac bypass had increased in-hospital mortality and complications. Age, comorbidity, and cardiac bypass were the strongest predictors of in-hospital mortality. Increasing surgeon volume, but not hospital volume, was associated with lower in-hospital mortality on multivariate regression analysis; however, this was not statistically significant.
CONCLUSION: Radical nephrectomy with associated IVC thrombectomy has significant complications and mortality. Surgeon but not hospital volume may affect outcomes.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23987150     DOI: 10.1016/j.urology.2013.04.054

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  15 in total

1.  [Level IV inferior vena cava tumor thrombus : A rare diagnosis in patients with renal cell carcinoma].

Authors:  L Hofer; C Gasch; G Hatiboglu; J Motsch; C Grüllich; S Duensing; M Hohenfellner
Journal:  Urologe A       Date:  2017-07       Impact factor: 0.639

2.  Assessment of healthcare quality metrics: Length-of-stay, 30-day readmission, and 30-day mortality for radical nephrectomy with inferior vena cava thrombectomy.

Authors:  Y Joseph Hwang; Brian J Minnillo; Simon P Kim; Robert Abouassaly
Journal:  Can Urol Assoc J       Date:  2015 Mar-Apr       Impact factor: 1.862

3.  The Significant Role of Tumor Volume on the Surgical Approach Choice, Surgical Complexity, and Postoperative Complications in Renal Cell Carcinoma With Venous Tumor Thrombus From a Large Chinese Center Experience.

Authors:  Qais Baheen; Zhuo Liu; Yichang Hao; Rejean R R Sawh; Yuxuan Li; Xun Zhao; Peng Hong; Zonglong Wu; Lulin Ma
Journal:  Front Oncol       Date:  2022-06-07       Impact factor: 5.738

Review 4.  Surgical treatment of renal cell carcinoma with inferior vena cava tumor thrombus.

Authors:  Shi-Min Yuan
Journal:  Surg Today       Date:  2022-01-03       Impact factor: 2.540

5.  Radical nephrectomy with resection of vena cava thrombus using extracorporeal circulation and deep hypothermic circulatory arrest.

Authors:  Gregory J Nason; Khaled Ajib; Guan Hee Tan; Dixon T S Woon; George T Christakis; Robert K Nam
Journal:  Can Urol Assoc J       Date:  2021-04       Impact factor: 1.862

6.  Precise control of caval and hepatic vessels: Surgical technique to treat level III caval thrombus concomitant to renal cell carcinoma.

Authors:  Ming Chen; Bin Xu; Ning Liu; Hua Jiang; Yiduo Wang; Yu Yang; Xiaowen Zhang; Chao Sun; Jing Liu; Weidong Zhu; Shuqiu Chen
Journal:  Can Urol Assoc J       Date:  2015-11-04       Impact factor: 1.862

Review 7.  Management of inferior vena cava tumor thrombus in locally advanced renal cell carcinoma.

Authors:  Sarah P Psutka; Bradley C Leibovich
Journal:  Ther Adv Urol       Date:  2015-08

Review 8.  [Limits of surgery in uro-oncology].

Authors:  A Heidenreich
Journal:  Urologe A       Date:  2018-09       Impact factor: 0.639

9.  Complex surgery and perioperative systemic therapy for genitourinary cancer of the retroperitoneum.

Authors:  A Finelli; N Coakley; J Chin; T A Flood; A Loblaw; C Morash; B Shayegan; R Siemens
Journal:  Curr Oncol       Date:  2020-02-01       Impact factor: 3.677

Review 10.  Influence of hospital volume on nephrectomy mortality and complications: a systematic review and meta-analysis stratified by surgical type.

Authors:  Ray C J Hsu; Theodosia Salika; Jonathan Maw; Georgios Lyratzopoulos; Vincent J Gnanapragasam; James N Armitage
Journal:  BMJ Open       Date:  2017-09-05       Impact factor: 2.692

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