Literature DB >> 23986144

Sugar furanoid trans-vicinal diacid as a γ-turn inducer: synthesis and conformational study.

Madhuri Vangala1, Snehal A Dhokale, Rupesh L Gawade, Rajamohanan R Pattuparambil, Vedavati G Puranik, Dilip D Dhavale.   

Abstract

A simple method for the synthesis of a sugar furanoid trans vicinal diacid and its incorporation into the N-terminal tetrapeptide sequence (H-Phe-Trp-Lys-Thr-OH) to get glycopeptide has been described. 2D NMR and MD simulation studies of clearly show that the sugar diacid adopts a γ-turn conformation towards the N-terminus.

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Year:  2013        PMID: 23986144     DOI: 10.1039/c3ob41462k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  3 in total

1.  AuBr3-catalyzed azidation of per-O-acetylated and per-O-benzoylated sugars.

Authors:  Jayashree Rajput; Srinivas Hotha; Madhuri Vangala
Journal:  Beilstein J Org Chem       Date:  2018-03-22       Impact factor: 2.883

2.  Synthesis of D-fructose-derived spirocyclic 2-substituted-2-oxazoline ribosides.

Authors:  Madhuri Vangala; Ganesh P Shinde
Journal:  Beilstein J Org Chem       Date:  2015-11-24       Impact factor: 2.883

3.  Sugar-derived oxazolone pseudotetrapeptide as γ-turn inducer and anion-selective transporter.

Authors:  Sachin S Burade; Sushil V Pawar; Tanmoy Saha; Navanath Kumbhar; Amol S Kotmale; Manzoor Ahmad; Pinaki Talukdar; Dilip D Dhavale
Journal:  Beilstein J Org Chem       Date:  2019-10-14       Impact factor: 2.883

  3 in total

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