Literature DB >> 239857

Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs.

M Schachter, E Karpinski, V Haines.   

Abstract

The histamine H2-receptor antagonist, metiamide, inhibits the acid gastric secretion produced by chloralose-urethane anaesthesia in dogs carrying gastric cannulae chronically. This secretion is also prevented by atropine and hexamethonium. "Spontaneous" gastric secretion of vagal origin in conscious dogs is also blocked by metiamide.

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Year:  1975        PMID： 239857     DOI： 10.1007/bf02358879

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  Anesthesia and gastric secretion.

Authors:  M SCHACHTER
Journal:  Am J Physiol       Date:  1949-02

2.  THE ABNORMAL FUNCTIONING OF THE GASTRIC SECRETORY MECHANISM AS A POSSIBLE FACTOR IN THE PATHOGENESIS OF PEPTIC ULCER.

Authors:  B P Babkin
Journal:  Can Med Assoc J       Date:  1938-05       Impact factor: 8.262

3.  Definition and antagonism of histamine H 2 -receptors.

Authors:  J W Black; W A Duncan; C J Durant; C R Ganellin; E M Parsons
Journal:  Nature       Date:  1972-04-21       Impact factor: 49.962

Review 4.  Histamine and gastric secretion: a later look, 1955-1965.

Authors:  C F Code
Journal:  Fed Proc       Date:  1965 Nov-Dec

5.  Metiamide--an orally active histamine H2-receptor antagonist.

Authors:  J W Black; W A Duncan; J C Emmett; C R Ganellin; T Hesselbo; M E Parsons; J H Wyllie
Journal:  Agents Actions       Date:  1973-10

6.  Inhibition of acid secretion in dog by metiamide, a histamine antagonist acting on H2 receptors.

Authors:  M I Grossman; S J Konturek
Journal:  Gastroenterology       Date:  1974-04       Impact factor: 22.682

7.  Actions of metiamide, an H2-histamine receptor antagonist, on gastric H+ and pepsin secretion in dogs.

Authors:  R Gibson; B I Hirschowitz; G Hutchison
Journal:  Gastroenterology       Date:  1974-07       Impact factor: 22.682
  7 in total
  1 in total

1.  The effect of anaesthesia on pentagastrin stimulated gastric acid secretion in the cat.

Authors:  M Albinus; E L Blair; B H Hirst; J D Reed
Journal:  J Physiol       Date:  1978-01       Impact factor: 5.182
  1 in total

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