Literature DB >> 23984836

Alcohol addiction: toward a patient-oriented pharmacological treatment.

Giovanni Addolorato1, Antonio Mirijello, Lorenzo Leggio.   

Abstract

Very few medications (i.e., disulfiram, naltrexone and acamprosate) are approved for the treatment of alcoholism and their effects are suboptimal. The development of new effective and safe pharmacological agents to treat alcoholic patients is crucial, together with the need to identify predictors of outcomes in different subsets of patients.

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Year:  2013        PMID： 23984836      PMCID： PMC4465082          DOI： 10.1517/14656566.2013.834047

Source DB:  PubMed          Journal:  Expert Opin Pharmacother        ISSN： 1465-6566            Impact factor:   3.889


  14 in total

Review 1.  Safety and efficacy of baclofen in the treatment of alcohol-dependent patients.

Authors:  Giovanni Addolorato; Lorenzo Leggio
Journal:  Curr Pharm Des       Date:  2010       Impact factor: 3.116

2.  Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate.

Authors:  F Kiefer; S H Witt; J Frank; A Richter; J Treutlein; T Lemenager; M M Nöthen; S Cichon; A Batra; M Berner; N Wodarz; U S Zimmermann; R Spanagel; K Wiedemann; M N Smolka; A Heinz; M Rietschel; K Mann
Journal:  Pharmacogenomics J       Date:  2010-06-29       Impact factor: 3.550

3.  Pharmacological relapse prevention of alcoholism: clinical predictors of outcome.

Authors:  Falk Kiefer; Hauke Helwig; Timo Tarnaske; Christian Otte; Holger Jahn; Klaus Wiedemann
Journal:  Eur Addict Res       Date:  2005       Impact factor: 3.015

4.  Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: A randomized controlled trial.

Authors:  B A Johnson; J D Roache; M A Javors; C C DiClemente; C R Cloninger; T J Prihoda; P S Bordnick; N Ait-Daoud; J Hensler
Journal:  JAMA       Date:  2000 Aug 23-30       Impact factor: 56.272

5.  Efficacy and safety of baclofen for alcohol dependence: a randomized, double-blind, placebo-controlled trial.

Authors:  James C Garbutt; Alexei B Kampov-Polevoy; Robert Gallop; Linda Kalka-Juhl; Barbara A Flannery
Journal:  Alcohol Clin Exp Res       Date:  2010-11       Impact factor: 3.455

6.  Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinking.

Authors:  Bankole A Johnson; Nassima Ait-Daoud; Chamindi Seneviratne; John D Roache; Martin A Javors; Xin-Qun Wang; Lei Liu; J Kim Penberthy; Carlo C DiClemente; Ming D Li
Journal:  Am J Psychiatry       Date:  2011-01-19       Impact factor: 18.112

7.  Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study.

Authors:  Giovanni Addolorato; Lorenzo Leggio; Anna Ferrulli; Silvia Cardone; Luisa Vonghia; Antonio Mirijello; Ludovico Abenavoli; Cristina D'Angelo; Fabio Caputo; Antonella Zambon; Paul S Haber; Giovanni Gasbarrini
Journal:  Lancet       Date:  2007-12-08       Impact factor: 79.321

8.  A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients.

Authors:  David W Oslin; Wade Berrettini; Henry R Kranzler; Helen Pettinati; Joel Gelernter; Joseph R Volpicelli; Charles P O'Brien
Journal:  Neuropsychopharmacology       Date:  2003-06-18       Impact factor: 7.853

9.  A within-group design of nontreatment seeking 5-HTTLPR genotyped alcohol-dependent subjects receiving ondansetron and sertraline.

Authors:  George A Kenna; William H Zywiak; John E McGeary; Lorenzo Leggio; Chinatsu McGeary; Shirley Wang; Andrea Grenga; Robert M Swift
Journal:  Alcohol Clin Exp Res       Date:  2008-11-19       Impact factor: 3.455

10.  An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study.

Authors:  Raymond F Anton; Gabor Oroszi; Stephanie O'Malley; David Couper; Robert Swift; Helen Pettinati; David Goldman
Journal:  Arch Gen Psychiatry       Date:  2008-02
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  2 in total

Review 1.  Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity.

Authors:  Anita Cservenka; Megan M Yardley; Lara A Ray
Journal:  Am J Addict       Date:  2016-11-04

2.  Correlates of Baclofen Effectiveness in Alcohol Dependence.

Authors:  Lekhansh Shukla; Tulika Shukla; Spandana Bokka; Arun Kandasamy; Vivek Benegal; Pratima Murthy; Prabhat Chand
Journal:  Indian J Psychol Med       Date:  2015 Jul-Sep
  2 in total

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