Literature DB >> 23984041

Chloroquine-induced Acute Dystonic Reactions after a Standard Therapeutic Dose for Uncomplicated Malaria.

Olusegun A Busari1, Joseph Fadare, Segun Agboola, Olusegun Gabriel, Olayide Elegbede, Yusuf Oladosu.   

Abstract

Acute dystonic reactions (ADR) are extrapyramidal effects that usually occur after the initiation of a wide variety of drugs or triggering factors besides neuroleptics. We report the case of a 54-year-old man who was admitted with an approximately 10-hour history of muscle twitching around the eyes, face and neck after he took the first dose of oral chloroquine phosphate (1 g [600 mg base]) prescribed for uncomplicated malaria. He was given intravenous diazepam (10 mg statum) followed by 10 mg of oral diazepam 3 times a day. The symptoms improved within 30 minutes of treatment, and he was discharged 14 hours later after a complete recovery.

Entities:  

Keywords:  Administration, Oral; Case Report; Chloroquine; Dystonia; Malaria; Nigeria; Reactions, acute

Year:  2013        PMID: 23984041      PMCID: PMC3749040          DOI: 10.12816/0003278

Source DB:  PubMed          Journal:  Sultan Qaboos Univ Med J        ISSN: 2075-051X


  15 in total

1.  Risks and benefits of chloroquine use in anticancer strategies.

Authors:  Andrea Savarino; Mothanje B Lucia; Flavio Giordano; Roberto Cauda
Journal:  Lancet Oncol       Date:  2006-10       Impact factor: 41.316

2.  Extrapyramidal syndrome following chloroquine therapy.

Authors:  S Singhi; P Singhi; M Singh
Journal:  Indian J Pediatr       Date:  1979-02       Impact factor: 1.967

Review 3.  The pathophysiology of extrapyramidal side-effects of neuroleptic drugs.

Authors:  C D Marsden; P Jenner
Journal:  Psychol Med       Date:  1980-02       Impact factor: 7.723

4.  Return of chloroquine antimalarial efficacy in Malawi.

Authors:  Miriam K Laufer; Phillip C Thesing; Nicole D Eddington; Rhoda Masonga; Fraction K Dzinjalamala; Shannon L Takala; Terrie E Taylor; Christopher V Plowe
Journal:  N Engl J Med       Date:  2006-11-09       Impact factor: 91.245

5.  Amodiaquine-associated adverse effects after inadvertent overdose and after a standard therapeutic dose.

Authors:  G O Adjei; B Q Goka; O P Rodrigues; L C G Hoegberg; M Alifrangis; Jal Kurtzhals
Journal:  Ghana Med J       Date:  2009-09

6.  Chloroquine transport via the malaria parasite's chloroquine resistance transporter.

Authors:  Rowena E Martin; Rosa V Marchetti; Anna I Cowan; Susan M Howitt; Stefan Bröer; Kiaran Kirk
Journal:  Science       Date:  2009-09-25       Impact factor: 47.728

7.  Chloroquine-induced acute dystonic reactions in the presence of metronidazole.

Authors:  J I Achumba; E I Ette; W O Thomas; E E Essien
Journal:  Drug Intell Clin Pharm       Date:  1988-04

8.  Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial.

Authors:  Julio Sotelo; Eduardo Briceño; Miguel Angel López-González
Journal:  Ann Intern Med       Date:  2006-03-07       Impact factor: 25.391

Review 9.  The varied clinical expressions of dystonia.

Authors:  S Fahn
Journal:  Neurol Clin       Date:  1984-08       Impact factor: 3.806

10.  Chloroquine resistance before and after its withdrawal in Kenya.

Authors:  Leah Mwai; Edwin Ochong; Abdi Abdirahman; Steven M Kiara; Steve Ward; Gilbert Kokwaro; Philip Sasi; Kevin Marsh; Steffen Borrmann; Margaret Mackinnon; Alexis Nzila
Journal:  Malar J       Date:  2009-05-18       Impact factor: 2.979

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  2 in total

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2.  Prolonged neuropsychiatric effects following management of chloroquine intoxication with psychotropic polypharmacy.

Authors:  Nicole M Maxwell; Remington L Nevin; Stephen Stahl; Jerald Block; Sarah Shugarts; Alan H B Wu; Stephen Dominy; Miguel Alonso Solano-Blanco; Sharon Kappelman-Culver; Christopher Lee-Messer; Jose Maldonado; Andrew J Maxwell
Journal:  Clin Case Rep       Date:  2015-04-09
  2 in total

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