Literature DB >> 23983970

Respiratory arrest and oversedation in an adolescent given intramuscular clonazepam for rapid tranquillization.

Jonathan Channing1, Simon Hill, Marion Wetherill, Oliver White.   

Abstract

Many young people in forensic adolescent units require intramuscular medication for rapid tranquillization. The efficacy and safety of the medications used is not well reported in this age group. Here we report a case of a 14-year-old girl experiencing severe oversedation and respiratory compromise on two occasions following intramuscular clonazepam.

Entities:  

Keywords:  adolescent; clonazepam; deep sedation; forensic psychiatry; respiratory depression

Year:  2012        PMID: 23983970      PMCID: PMC3736938          DOI: 10.1177/2045125312449012

Source DB:  PubMed          Journal:  Ther Adv Psychopharmacol        ISSN: 2045-1253


  12 in total

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3.  Pharmacokinetics of the anticonvulsant drug clonazepam evaluated from single oral and intravenous doses and by repeated oral administration.

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Journal:  Eur J Clin Pharmacol       Date:  1975-12-19       Impact factor: 2.953

4.  Rectal Flumazenil can save the day.

Authors:  Denisa Haret
Journal:  Paediatr Anaesth       Date:  2008-04       Impact factor: 2.556

5.  The fallacy of a lifesaving sublingual injection of flumazenil.

Authors:  Joel M Weaver
Journal:  Anesth Prog       Date:  2011

6.  Where has all the lorazepam gone?

Authors:  David J S de Monteverde-Robb; Christopher M C Allen; Maxwell S Damian; Mark R A Manford; Rowan M Burnstein; Kevin E J Gunning; David K Menon
Journal:  BMJ       Date:  2011-09-20

Review 7.  [Rapid tranquillisation; review of the literature and recommendations].

Authors:  M Bak; J van Os; M Marcelis
Journal:  Tijdschr Psychiatr       Date:  2011

8.  Incidents in an adolescent forensic secure inpatient service.

Authors:  Simon A Hill; Oliver White; Joanne Lolley; Alia Sidki-Gomez; Helen Williams
Journal:  Med Sci Law       Date:  2011-11-25       Impact factor: 1.266

9.  Comparative single-dose pharmacokinetics of clonazepam following intravenous, intramuscular and oral administration to healthy volunteers.

Authors:  C Crevoisier; M C Delisle; I Joseph; G Foletti
Journal:  Eur Neurol       Date:  2003       Impact factor: 1.710

10.  Clonazepam and lorazepam in acute mania: a Bayesian meta-analysis.

Authors:  François Curtin; Pierre Schulz
Journal:  J Affect Disord       Date:  2004-03       Impact factor: 4.839

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