| Literature DB >> 23983933 |
Ahmed Mahmoud1, Karen P Hayhurst, Richard J Drake, Shôn W Lewis, Thomas R E Barnes.
Abstract
Antipsychotic nonneurological side effects, such as sexual dysfunction, can adversely affect the quality of patients' relationships, their treatment adherence and their quality of life. In the UK CUtLASS (Cost Utility of the Latest Antipsychotics in Severe Schizophrenia) study, nonneurological side effects were assessed using the ANNSERSv1 (Antipsychotic Non-Neurological Side Effects Rating Scale version 1), a new scale to assess the side effects associated with both first- and second-generation antipsychotic drugs. A total of 26 participants also completed the Derogatis Interview for Sexual Functioning (self-report version, DISF-SR). A statistically significant, and specific, correlation was found between scores on the DISF-SR and the sexual side-effect section of the ANNSERS at baseline. The sexual side-effects subscale of the ANNSERS is a valid measure of sexual dysfunction in the treatment of schizophrenia.Entities:
Keywords: adverse effects; antipsychotics; assessment; schizophrenia; sexual dysfunction
Year: 2011 PMID: 23983933 PMCID: PMC3736922 DOI: 10.1177/2045125311417041
Source DB: PubMed Journal: Ther Adv Psychopharmacol ISSN: 2045-1253