Literature DB >> 23983850

Update in intracerebral hemorrhage.

Maria I Aguilar1, Thomas G Brott.   

Abstract

Spontaneous, nontraumatic intracerebral hemorrhage (ICH) is defined as bleeding within the brain parenchyma. Intracranial hemorrhage includes bleeding within the cranial vault and encompasses ICH, subdural hematoma, epidural bleeds, and subarachnoid hemorrhage (SAH). This review will focus only on ICH. This stroke subtype accounts for about 10% of all strokes. The hematoma locations are deep or ganglionic, lobar, cerebellar, and brain stem in descending order of frequency. Intracerebral hemorrhage occurs twice as common as SAH and is equally as deadly. Risk factors for ICH include hypertension, cerebral amyloid angiopathy, advanced age, antithrombotic therapy and history of cerebrovascular disease. The clinical presentation is "stroke like" with sudden onset of focal neurological deficits. Noncontrast head computerized tomography (CT) scan is the standard diagnostic tool. However, newer neuroimaging techniques have improved the diagnostic yield in terms of underlying pathophysiology and may aid in prognosis. Intracerebral hemorrhage is a neurological emergency. Medical care begins with stabilization of airway, breathing function, and circulation (ABCs), followed by specific measures aimed to decrease secondary neurological damage and to prevent both medical and neurological complications. Reversal of coagulopathy when present is of the essence. Blood pressure management can be key and continues as an area of debate and ongoing research. Surgical evacuation of ICH is of unproven benefit though a subset of well-selected patients may have improved outcomes. Ventriculostomy and intracranial pressure (ICP) monitoring are interventions also used in this patient population. To date, hemostatic medications and neuroprotectants have failed to result in clinical improvement. A multidisciplinary approach is recommended, with participation of vascular neurology, vascular neurosurgery, critical care, and rehabilitation medicine as the main players.

Entities:  

Keywords:  diagnosis; intracerebral hemorrhage; prognosis; surgery; treatment

Year:  2011        PMID: 23983850      PMCID: PMC3726132          DOI: 10.1177/1941875211409050

Source DB:  PubMed          Journal:  Neurohospitalist        ISSN: 1941-8744


  93 in total

1.  Prothrombin complex concentrates: indications, contraindications, and risks: a task force summary.

Authors:  P Hellstern; W M Halbmayer; M Köhler; R Seitz; G Müller-Berghaus
Journal:  Thromb Res       Date:  1999-08-15       Impact factor: 3.944

2.  High-dose atorvastatin after stroke or transient ischemic attack.

Authors:  Pierre Amarenco; Julien Bogousslavsky; Alfred Callahan; Larry B Goldstein; Michael Hennerici; Amy E Rudolph; Henrik Sillesen; Lisa Simunovic; Michael Szarek; K M A Welch; Justin A Zivin
Journal:  N Engl J Med       Date:  2006-08-10       Impact factor: 91.245

3.  Early metabolic alterations in edematous perihematomal brain regions following experimental intracerebral hemorrhage.

Authors:  K R Wagner; G Xi; Y Hua; M Kleinholz; G M de Courten-Myers; R E Myers
Journal:  J Neurosurg       Date:  1998-06       Impact factor: 5.115

4.  Correction for partial volume effects in regional blood flow measurements adjacent to hematomas in humans with intracerebral hemorrhage: implementation and validation.

Authors:  T O Videen; J E Dunford-Shore; M N Diringer; W J Powers
Journal:  J Comput Assist Tomogr       Date:  1999 Mar-Apr       Impact factor: 1.826

5.  Leukoaraiosis, intracerebral hemorrhage, and arterial hypertension.

Authors:  D Inzitari; G P Giordano; A L Ancona; G Pracucci; M Mascalchi; L Amaducci
Journal:  Stroke       Date:  1990-10       Impact factor: 7.914

6.  Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.

Authors:  Lewis B Morgenstern; J Claude Hemphill; Craig Anderson; Kyra Becker; Joseph P Broderick; E Sander Connolly; Steven M Greenberg; James N Huang; R Loch MacDonald; Steven R Messé; Pamela H Mitchell; Magdy Selim; Rafael J Tamargo
Journal:  Stroke       Date:  2010-07-22       Impact factor: 7.914

7.  Recurrence of bleeding in patients with hypertensive intracerebral hemorrhage.

Authors:  H Bae; D Jeong; J Doh; K Lee; I Yun; B Byun
Journal:  Cerebrovasc Dis       Date:  1999 Mar-Apr       Impact factor: 2.762

8.  Relationship between white-matter hyperintensities and hematoma volume and growth in patients with intracerebral hemorrhage.

Authors:  Min Lou; Adel Al-Hazzani; Richard P Goddeau; Vera Novak; Magdy Selim
Journal:  Stroke       Date:  2009-11-19       Impact factor: 7.914

9.  The radiological (CT) and clinical sequelae of primary intracerebral haemorrhage.

Authors:  L Kreel; R Kay; J Woo; H Y Wong; M G Nicholls
Journal:  Br J Radiol       Date:  1991-12       Impact factor: 3.039

10.  Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial.

Authors:  Craig S Anderson; Yining Huang; Ji Guang Wang; Hisatomi Arima; Bruce Neal; Bin Peng; Emma Heeley; Christian Skulina; Mark W Parsons; Jong Sung Kim; Qing Ling Tao; Yue Chun Li; Jian Dong Jiang; Li Wen Tai; Jin Li Zhang; En Xu; Yan Cheng; Stephane Heritier; Lewis B Morgenstern; John Chalmers
Journal:  Lancet Neurol       Date:  2008-04-07       Impact factor: 44.182

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  36 in total

1.  Effect of Frequency and Focal Spacing on Transcranial Histotripsy Clot Liquefaction, Using Electronic Focal Steering.

Authors:  Tyler Gerhardson; Jonathan R Sukovich; Aditya S Pandey; Timothy L Hall; Charles A Cain; Zhen Xu
Journal:  Ultrasound Med Biol       Date:  2017-07-14       Impact factor: 2.998

2.  Racial/ethnic variation of APOE alleles for lobar intracerebral hemorrhage.

Authors:  Russell P Sawyer; Padmini Sekar; Jennifer Osborne; Steven J Kittner; Charles J Moomaw; Matthew L Flaherty; Carl D Langefeld; Christopher D Anderson; Jonathan Rosand; Daniel Woo
Journal:  Neurology       Date:  2018-06-29       Impact factor: 9.910

Review 3.  The impact of prothrombin complex concentrates when treating DOAC-associated bleeding: a review.

Authors:  Maureane Hoffman; Joshua N Goldstein; Jerrold H Levy
Journal:  Int J Emerg Med       Date:  2018-12-03

Review 4.  Hemorrhagic and non-hemorrhagic causes of signal loss on susceptibility-weighted imaging.

Authors:  Kamila A Skalski; Alexander T Kessler; Alok A Bhatt
Journal:  Emerg Radiol       Date:  2018-08-22

5.  A composite neurobehavioral test to evaluate acute functional deficits after cerebellar haemorrhage in rats.

Authors:  Devin W McBride; Derek Nowrangi; Harpreet Kaur; Guangyong Wu; Lei Huang; Tim Lekic; Jiping Tang; John H Zhang
Journal:  J Cereb Blood Flow Metab       Date:  2017-03-20       Impact factor: 6.200

Review 6.  Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage.

Authors:  Jing Chen-Roetling; Raymond F Regan
Journal:  Curr Pharm Des       Date:  2017       Impact factor: 3.116

7.  A Case of Recurrent Lobar Intracerebral Hemorrhage in the Setting of Phosphodiesterase-5 Inhibitor Use.

Authors:  Scott A Lucchese; Arshdeep S Dhaliwal; Arpanjeet Kaur; Laura Qi
Journal:  Mo Med       Date:  2019 Sep-Oct

Review 8.  A Multi-Model Pipeline for Translational Intracerebral Haemorrhage Research.

Authors:  Sarah E Withers; Adrian R Parry-Jones; Stuart M Allan; Paul R Kasher
Journal:  Transl Stroke Res       Date:  2020-07-07       Impact factor: 6.829

Review 9.  The Pathophysiology of Intracerebral Hemorrhage Formation and Expansion.

Authors:  Frieder Schlunk; Steven M Greenberg
Journal:  Transl Stroke Res       Date:  2015-06-16       Impact factor: 6.829

Review 10.  Cognitive impairment before and after intracerebral haemorrhage: a systematic review.

Authors:  Claire Donnellan; David Werring
Journal:  Neurol Sci       Date:  2019-12-04       Impact factor: 3.307

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