Literature DB >> 23982395

Revision osteochondral allograft transplantations: do they work?

Melissa T Horton1, Pamela A Pulido, Julie C McCauley, William D Bugbee.   

Abstract

BACKGROUND: Primary fresh osteochondral allograft transplantation is a useful treatment option for osteochondral lesions in the knee. Clinical failure of primary osteochondral allograft transplantation may require further surgery, including revision osteochondral allograft transplantation.
PURPOSE: To evaluate outcomes of patients who have undergone revision osteochondral allograft transplantation of the knee. STUDY
DESIGN: Case series; Level of evidence, 4.
METHODS: This series included 33 patients (33 knees) who underwent revision osteochondral allograft transplantation between 1983 and 2012, were at least 2 years out from surgery, and had a minimum 2-year follow-up. Clinical evaluations included the International Knee Documentation Committee pain, function, and total scores; Knee Society function score; and modified Merle d'Aubigné and Postel scale. Failure of the revision allograft was defined as conversion to partial or total knee arthroplasty.
RESULTS: The mean follow-up after revision osteochondral allograft transplantation was 10 years, with 75% of patients having more than 5 years' follow-up. Thirteen patients (39%) had failed results after revision osteochondral allograft transplantation, with a mean time to failure of 5.5 years. The remaining 20 patients (61%) had surviving revision allografts, with a mean graft survival of 10 years. Mean pain and function scores at the last follow-up were improved. Survivorship of the revision allograft was 61% at 10 years.
CONCLUSION: Revision osteochondral allograft transplantation of the knee demonstrated acceptable clinical outcomes, although they were inferior to primary allograft transplantation procedures. Revision osteochondral allograft transplantation may be considered an option for patients with a failed primary osteochondral allograft.

Entities:  

Keywords:  allografts; articular cartilage; knee; osteochondral graft failure; primary osteochondral allograft; revision osteochondral allograft

Mesh:

Year:  2013        PMID: 23982395     DOI: 10.1177/0363546513500628

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  13 in total

1.  Osteochondral allograft.

Authors:  Arissa M Torrie; William W Kesler; Joshua Elkin; Robert A Gallo
Journal:  Curr Rev Musculoskelet Med       Date:  2015-12

2.  Clinical Outcomes after Revision of Autologous Chondrocyte Implantation to Osteochondral Allograft Transplantation for Large Chondral Defects: A Comparative Matched-Group Analysis.

Authors:  Gergo Merkely; Takahiro Ogura; Jakob Ackermann; Alexandre Barbieri Mestriner; Andreas H Gomoll
Journal:  Cartilage       Date:  2019-03-22       Impact factor: 4.634

3.  Combined osteochondral allograft and meniscal allograft transplantation: a survivorship analysis.

Authors:  Alan Getgood; Jonathon Gelber; Simon Gortz; Alison De Young; William Bugbee
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-02-12       Impact factor: 4.342

Review 4.  Osteochondral allograft transplantation in cartilage repair: Graft storage paradigm, translational models, and clinical applications.

Authors:  William D Bugbee; Andrea L Pallante-Kichura; Simon Görtz; David Amiel; Robert Sah
Journal:  J Orthop Res       Date:  2015-09-24       Impact factor: 3.494

Review 5.  How to Manage a Failed Cartilage Repair: A Systematic Literature Review.

Authors:  Donato Rosa; Sigismondo Luca Di Donato; Giovanni Balato; Alessio D'Addona; Francesco Smeraglia; Gaetano Correra; Gianni Di Vico
Journal:  Joints       Date:  2017-07-28

Review 6.  Treatment of Failed Articular Cartilage Reconstructive Procedures of the Knee: A Systematic Review.

Authors:  Joseph D Lamplot; Kevin A Schafer; Matthew J Matava
Journal:  Orthop J Sports Med       Date:  2018-03-23

7.  Learning From Failure in Cartilage Repair Surgery: An Analysis of the Mode of Failure of Primary Procedures in Consecutive Cases at a Tertiary Referral Center.

Authors:  Aaron J Krych; Mario Hevesi; Vishal S Desai; Christopher L Camp; Michael J Stuart; Daniel B F Saris
Journal:  Orthop J Sports Med       Date:  2018-05-17

Review 8.  Joint Preservation Techniques in Orthopaedic Surgery.

Authors:  Philip J York; Frank B Wydra; Matthew E Belton; Armando F Vidal
Journal:  Sports Health       Date:  2017-06-20       Impact factor: 3.843

9.  The cost-effectiveness of osteochondral allograft transplantation in the knee.

Authors:  Hema Mistry; Andrew Metcalfe; Nick Smith; Emma Loveman; Jill Colquitt; Pamela Royle; Norman Waugh
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2019-02-05       Impact factor: 4.342

10.  Metrics of OsteoChondral Allografts (MOCA) Group Consensus Statements on the Use of Viable Osteochondral Allograft.

Authors:  Simon Görtz; Suzanne M Tabbaa; Deryk G Jones; John D Polousky; Dennis C Crawford; William D Bugbee; Brian J Cole; Jack Farr; James E Fleischli; Alan Getgood; Andreas H Gomoll; Allan E Gross; Aaron J Krych; Christian Lattermann; Bert R Mandelbaum; Peter R Mandt; Raffy Mirzayan; Timothy S Mologne; Matthew T Provencher; Scott A Rodeo; Oleg Safir; Eric D Strauss; Christopher J Wahl; Riley J Williams; Adam B Yanke
Journal:  Orthop J Sports Med       Date:  2021-03-23
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