Literature DB >> 23982006

Patients with autosomal dominant spinocerebellar ataxia have more risk of falls, important balance impairment, and decreased ability to function.

Carolina Yuri P Aizawa1, José Luiz Pedroso, Pedro Braga-Neto, Marilia Rezende Callegari, Orlando Graziani Povoas Barsottini.   

Abstract

OBJECTIVES: To assess balance and ability to function in patients with spinocerebellar ataxia.
METHODS: A total of 44 patients with different spinocerebellar ataxia types 1, 2, 3, and 6 were evaluated using the Tinetti balance and gait assessment and the functional independence measure. The scale for the assessment and rating of ataxia and the international cooperative ataxia rating scale were used to evaluate disease severity.
RESULTS: Most patients showed significant risk of falls. The balance scores were significantly different in spinocerebellar ataxia types. A significant positive correlation between balance and disease severity was found.
CONCLUSION: Patients with spinocerebellar ataxia have important balance impairment and risk of falls that influence the ability to function such as self-care, transfers, and locomotion. Furthermore, the more severe ataxia is, the more compromised are postural balance, risk of falls, and ability to function.

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Mesh:

Year:  2013        PMID: 23982006     DOI: 10.1590/0004-282X20130094

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  4 in total

Review 1.  Current concepts in the treatment of hereditary ataxias.

Authors:  Pedro Braga Neto; José Luiz Pedroso; Sheng-Han Kuo; C França Marcondes Junior; Hélio Afonso Ghizoni Teive; Orlando Graziani Povoas Barsottini
Journal:  Arq Neuropsiquiatr       Date:  2016-03       Impact factor: 1.420

2.  Multimodal Mobility Assessment Predicts Fall Frequency and Severity in Cerebellar Ataxia.

Authors:  Roman Schniepp; Anna Huppert; Julian Decker; Fabian Schenkel; Marianne Dieterich; Thomas Brandt; Max Wuehr
Journal:  Cerebellum       Date:  2022-02-04       Impact factor: 3.847

3.  Local Stability of the Trunk in Patients with Degenerative Cerebellar Ataxia During Walking.

Authors:  Giorgia Chini; Alberto Ranavolo; Francesco Draicchio; Carlo Casali; Carmela Conte; Giovanni Martino; Luca Leonardi; Luca Padua; Gianluca Coppola; Francesco Pierelli; Mariano Serrao
Journal:  Cerebellum       Date:  2017-02       Impact factor: 3.847

4.  Anteroposterior Stability: A Determinant of Gait Dysfunction and Falls in Spinocerebellar Ataxia.

Authors:  V S Ganapathy; Tittu T James; Mariamma Philip; Nitish Kamble; Amitabh Bhattacharya; Pradnya Dhargave; Pramod Kumar Pal
Journal:  Ann Indian Acad Neurol       Date:  2021-05-21       Impact factor: 1.383

  4 in total

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