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8 in total

1. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.

Authors: Jonathan C Cohen; Eric Boerwinkle; Thomas H Mosley; Helen H Hobbs
Journal: N Engl J Med Date: 2006-03-23 Impact factor: 91.245

2. A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts.

Authors: R G Anderson; J L Goldstein; M S Brown
Journal: Nature Date: 1977 Dec 22-29 Impact factor: 49.962

3. Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein.

Authors: M S Brown; J L Goldstein
Journal: Cell Date: 1976-12 Impact factor: 41.582

Review 4. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor.

Authors: M S Brown; J L Goldstein
Journal: Cell Date: 1997-05-02 Impact factor: 41.582

Review 5. The presenilins in Alzheimer's disease--proteolysis holds the key.

Authors: C Haass; B De Strooper
Journal: Science Date: 1999-10-29 Impact factor: 47.728

6. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.

Authors: B De Strooper; W Annaert; P Cupers; P Saftig; K Craessaerts; J S Mumm; E H Schroeter; V Schrijvers; M S Wolfe; W J Ray; A Goate; R Kopan
Journal: Nature Date: 1999-04-08 Impact factor: 49.962

7. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.

Authors: J Ye; R B Rawson; R Komuro; X Chen; U P Davé; R Prywes; M S Brown; J L Goldstein
Journal: Mol Cell Date: 2000-12 Impact factor: 17.970

8. Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.

Authors: M S Brown; J L Goldstein
Journal: Proc Natl Acad Sci U S A Date: 1974-03 Impact factor: 11.205

8 in total

5 in total

Brown and Goldstein: the cholesterol chronicles.

1. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.

2. A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts.

3. Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein.

Review 4. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor.

Review 5. The presenilins in Alzheimer's disease--proteolysis holds the key.

6. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.

7. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.

8. Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.

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2. NHLBI strategic visioning: setting an agenda together for the NHLBI of 2025.

3. National Heart, Lung, and Blood Institute Strategic Visioning: setting an agenda together for the NHLBI of 2025.

4. An Allosteric Binding Site on Sortilin Regulates the Trafficking of VLDL, PCSK9, and LDLR in Hepatocytes.

5. Single case designs for early phase behavioral translational research in health psychology.