Literature DB >> 2397973

Once-daily naftifine cream 1% in the treatment of tinea cruris and tinea corporis.

R E Jordon1, R P Rapini, I H Rex, H I Katz, J G Hickman, J W Bard, R S Medansky, D A Lew-Kaya, J Sefton, R E DeGryse.   

Abstract

Seventy patients with tinea cruris or tinea corporis were treated with naftifine cream 1% or vehicle once daily for 4 weeks in this double-blind, randomized study. After two weeks, the patients using naftifine had a significantly higher mycologic cure rate than the vehicle-treated patients (79% vs. 31%, p less than 0.001), and they showed significantly better resolution of signs and symptoms. Statistically significantly differences favoring naftifine over its vehicle were found throughout the treatment period and 2 weeks posttreatment.

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Year:  1990        PMID: 2397973     DOI: 10.1111/j.1365-4362.1990.tb03835.x

Source DB:  PubMed          Journal:  Int J Dermatol        ISSN: 0011-9059            Impact factor:   2.736


  2 in total

Review 1.  An overview of topical antifungal therapy in dermatomycoses. A North American perspective.

Authors:  A K Gupta; T R Einarson; R C Summerbell; N H Shear
Journal:  Drugs       Date:  1998-05       Impact factor: 9.546

Review 2.  Naftifine. A review of its antimicrobial activity and therapeutic use in superficial dermatomycoses.

Authors:  J P Monk; R N Brogden
Journal:  Drugs       Date:  1991-10       Impact factor: 9.546

  2 in total

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