| Literature DB >> 23978357 |
Quan V Vo1, Craige Trenerry, Simone Rochfort, Jenny Wadeson, Carolina Leyton, Andrew B Hughes.
Abstract
Aromatic GLs are important members of the glucosinolate family of compounds because of their potential biological activity and medicinal properties. This study has shown success in the high yielding synthesis of some important aromatic GLs as well as the results of testing for anti-inflammatory properties of the synthetic GLs. 3,4-Dimethoxyphenylglucosinolate was found to be the most active anti-inflammatory of the seven glucosinolates assayed.Entities:
Keywords: 1,2-dimethoxyethane; 3,4-Dimethoxyphenylglucosinolate; Anti-inflammatory; Aromatic glucosinolate; Brassica; DCM; DME; DMF; ELISA; ESI; FTMS; GLs; HESI; HRMS; IR; LPS; MS; N,N-dimethylformamide; N-chlorosuccinimide; NCS; NMR; PMA; THF; TLC; TNF-α; TNFalpha; UV; Z; benzyloxycarbonyl; dichloromethane; electrospray ionization; enzyme-linked immunosorbent assay; fourier transform mass spectrometry; glucosinolates; heated electrospray ionization; high resolution mass spectrometry; infra-red; lipopolysaccharides; mass spectrometry; nuclear magnetic resonance; phorbol-12-myristate-13-acetate; tetrahydrofuran; thin layer chromatography; tumor necrosis factor alpha; ultra-violet
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Year: 2013 PMID： 23978357 DOI： 10.1016/j.bmc.2013.07.049
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641