| Literature DB >> 23977433 |
Anselm Wang-Hei Hui1, Hon-Wai Lau, Tiffany Hoi-Tung Chan, Stephen Kwok-Wing Tsui.
Abstract
Advancements in next generation sequencing technology have provided means for the comprehensive profiling of the microbial community in the respiratory tract in both physiological and pathological conditions. Recent studies have analyzed the bacterial composition in the respiratory tract of chronic obstructive pulmonary disease (COPD), influenza and tuberculosis patients, and have identified novel targets that may potentially lead to secondary infections. Certain bacteria have also been found to regulate the lung immune system and have unexpected connections with respiratory diseases. Further studies in these areas are necessary to dissect the exact relationship between the dynamics of the microbiota and the health of the respiratory system.Entities:
Keywords: Human microbiota; chronic obstructive pulmonary disease (COPD); influenza; next generation sequencing; thoracic diseases; tuberculosis
Year: 2013 PMID: 23977433 PMCID: PMC3747530 DOI: 10.3978/j.issn.2072-1439.2013.07.41
Source DB: PubMed Journal: J Thorac Dis ISSN: 2072-1439 Impact factor: 2.895