Literature DB >> 23975930

A flexible polyglutamine hinge opens new doors for understanding huntingtin function.

Flaviano Giorgini1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23975930      PMCID： PMC3767501          DOI： 10.1073/pnas.1313668110

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


× No keyword cloud information.
  20 in total

1.  Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy.

Authors:  A R La Spada; E M Wilson; D B Lubahn; A E Harding; K H Fischbeck
Journal:  Nature       Date:  1991-07-04       Impact factor: 49.962

Review 2.  History of genetic disease: the molecular genetics of Huntington disease - a history.

Authors:  Gillian P Bates
Journal:  Nat Rev Genet       Date:  2005-10       Impact factor: 53.242

Review 3.  Mouse models of Huntington's disease.

Authors:  Liliana B Menalled; Marie-Françoise Chesselet
Journal:  Trends Pharmacol Sci       Date:  2002-01       Impact factor: 14.819

4.  PACSIN, a brain protein that is upregulated upon differentiation into neuronal cells.

Authors:  M Plomann; R Lange; G Vopper; H Cremer; U A Heinlein; S Scheff; S A Baldwin; M Leitges; M Cramer; M Paulsson; D Barthels
Journal:  Eur J Biochem       Date:  1998-08-15

5.  Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.

Authors:  M DiFiglia; E Sapp; K O Chase; S W Davies; G P Bates; J P Vonsattel; N Aronin
Journal:  Science       Date:  1997-09-26       Impact factor: 47.728

6.  A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Authors: 
Journal:  Cell       Date:  1993-03-26       Impact factor: 41.582

7.  Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.

Authors:  E Scherzinger; R Lurz; M Turmaine; L Mangiarini; B Hollenbach; R Hasenbank; G P Bates; S W Davies; H Lehrach; E E Wanker
Journal:  Cell       Date:  1997-08-08       Impact factor: 41.582

8.  Endocytosis and synaptic removal of NR3A-containing NMDA receptors by PACSIN1/syndapin1.

Authors:  Isabel Pérez-Otaño; Rafael Luján; Steven J Tavalin; Markus Plomann; Jan Modregger; Xiao-Bo Liu; Edward G Jones; Stephen F Heinemann; Donald C Lo; Michael D Ehlers
Journal:  Nat Neurosci       Date:  2006-04-16       Impact factor: 24.884

9.  Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin.

Authors:  Nicholas Stephane Caron; Carly Robyn Desmond; Jianrun Xia; Ray Truant
Journal:  Proc Natl Acad Sci U S A       Date:  2013-07-29       Impact factor: 11.205

10.  PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains.

Authors:  Jan Modregger; Nicholas A DiProspero; Vinod Charles; Danilo A Tagle; Markus Plomann
Journal:  Hum Mol Genet       Date:  2002-10-01       Impact factor: 6.150
View more
  5 in total

Review 1.  Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities.

Authors:  Rachel J Harding; Yu-Feng Tong
Journal:  Acta Pharmacol Sin       Date:  2018-04-05       Impact factor: 6.150

2.  Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status.

Authors:  Kevin K Kumar; Cody R Goodwin; Michael A Uhouse; Julia Bornhorst; Tanja Schwerdtle; Michael Aschner; John A McLean; Aaron B Bowman
Journal:  Metallomics       Date:  2015-02       Impact factor: 4.526

3.  Effects of flanking sequences and cellular context on subcellular behavior and pathology of mutant HTT.

Authors:  Anjalika Chongtham; Douglas J Bornemann; Brett A Barbaro; Tamas Lukacsovich; Namita Agrawal; Adeela Syed; Shane Worthge; Judith Purcell; John Burke; Theodore M Chin; J Lawrence Marsh
Journal:  Hum Mol Genet       Date:  2020-03-13       Impact factor: 6.150

Review 4.  Huntington's Disease-An Outlook on the Interplay of the HTT Protein, Microtubules and Actin Cytoskeletal Components.

Authors:  Aleksandra S Taran; Lilia D Shuvalova; Maria A Lagarkova; Irina B Alieva
Journal:  Cells       Date:  2020-06-22       Impact factor: 6.600

5.  Conformational studies of pathogenic expanded polyglutamine protein deposits from Huntington's disease.

Authors:  Irina Matlahov; Patrick Ca van der Wel
Journal:  Exp Biol Med (Maywood)       Date:  2019-06-15
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.