Mary A S Melo1, Weslanny A Morais1, Vanara F Passos2, Juliana P M Lima1, Lidiany K A Rodrigues3. 1. Post-graduate Program in Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, 944 Cap Francisco Pedro Street-Rodolfo Teófilo, Fortaleza, Ceará, 60430-170, Brazil. 2. School of Dentistry, University of Fortaleza, Washington Soares Avenue,1321, Fortaleza, Ceará, 60811-905, Brazil. 3. Post-graduate Program in Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, 944 Cap Francisco Pedro Street-Rodolfo Teófilo, Fortaleza, Ceará, 60430-170, Brazil. lidianykarla@yahoo.com.
Abstract
INTRODUCTION: Fluoride-containing materials have been suggested to control enamel demineralization around orthodontic brackets during the treatment with fixed appliances. The improvement of their properties has been made through innovations, such as the application of nanotechnology by incorporation of nanofillers. OBJECTIVE: This in vitro study evaluated the capacity of fluoride releasing and enamel demineralization inhibition of fluoride-releasing nanofilled cement around orthodontic brackets using an artificial caries biofilm model. MATERIALS AND METHODS: Forty bovine enamel discs were selected by evaluating surface microhardness and randomized into four groups (n = 10): non-fluoride-releasing microfilled composite, fluoride-releasing microfilled composite, resin-modified glass ionomer cement (RMGI), and fluoride-releasing nanofilled composite (FN). After brackets bonding in each disc, the specimens were subjected to a cariogenic challenge through a Streptococcus mutans biofilm model. After the experimental period, the biofilm formed around the brackets was collected for fluoride analysis and the mineral loss around the brackets was determined by integrated demineralization via cross-sectional microhardness measurement at 20 and 70 μm from the bracket margin. Additionally, samples of each group were subjected to energy-dispersive X-ray spectroscopy (EDX) analysis examined under a scanning electron microscopy (SEM). ANOVA followed by Tukey test were applied for fluoride concentration and mineral loss data, respectively. RESULTS: At both distances, only RMGI statistically differed from the other groups presenting the lowest demineralization, although there was a trend to a lower demineralization of enamel around brackets in FN group. Similar condition was found to fluoride concentration and EDX/SEM analysis. CONCLUSIONS: Under the cariogenic exposure condition of this study, the fluoride-releasing nanofilled material had similar performance to fluoride-releasing microfilled materials. CLINICAL RELEVANCE: The presence of nanofillers in the fluoride-releasing materials studied did not promote further benefits against caries lesion development around brackets and presented inferior demineralization inhibition than the resin-modified glass ionomer material.
INTRODUCTION:Fluoride-containing materials have been suggested to control enamel demineralization around orthodontic brackets during the treatment with fixed appliances. The improvement of their properties has been made through innovations, such as the application of nanotechnology by incorporation of nanofillers. OBJECTIVE: This in vitro study evaluated the capacity of fluoride releasing and enamel demineralization inhibition of fluoride-releasing nanofilled cement around orthodontic brackets using an artificial caries biofilm model. MATERIALS AND METHODS: Forty bovine enamel discs were selected by evaluating surface microhardness and randomized into four groups (n = 10): non-fluoride-releasing microfilled composite, fluoride-releasing microfilled composite, resin-modified glass ionomer cement (RMGI), and fluoride-releasing nanofilled composite (FN). After brackets bonding in each disc, the specimens were subjected to a cariogenic challenge through a Streptococcus mutans biofilm model. After the experimental period, the biofilm formed around the brackets was collected for fluoride analysis and the mineral loss around the brackets was determined by integrated demineralization via cross-sectional microhardness measurement at 20 and 70 μm from the bracket margin. Additionally, samples of each group were subjected to energy-dispersive X-ray spectroscopy (EDX) analysis examined under a scanning electron microscopy (SEM). ANOVA followed by Tukey test were applied for fluoride concentration and mineral loss data, respectively. RESULTS: At both distances, only RMGI statistically differed from the other groups presenting the lowest demineralization, although there was a trend to a lower demineralization of enamel around brackets in FN group. Similar condition was found to fluoride concentration and EDX/SEM analysis. CONCLUSIONS: Under the cariogenic exposure condition of this study, the fluoride-releasing nanofilled material had similar performance to fluoride-releasing microfilled materials. CLINICAL RELEVANCE: The presence of nanofillers in the fluoride-releasing materials studied did not promote further benefits against caries lesion development around brackets and presented inferior demineralization inhibition than the resin-modified glass ionomer material.
Authors: Paula Passalini; Tatiana Kelly da Silva Fidalgo; Erika Machado Caldeira; Rogério Gleiser; Matilde da Cunha Gonçalves Nojima; Lucianne Cople Maia Journal: Braz Oral Res Date: 2010 Apr-Jun
Authors: Aniek Derks; Anne Marie Kuijpers-Jagtman; Jo E Frencken; Martin A Van't Hof; Christos Katsaros Journal: Am J Orthod Dentofacial Orthop Date: 2007-08 Impact factor: 2.650
Authors: Mervyn Y H Chin; Andrew Sandham; Elena N Rumachik; Jan L Ruben; Marie-Charlotte D N J M Huysmans Journal: Am J Orthod Dentofacial Orthop Date: 2009-10 Impact factor: 2.650
Authors: Sonja Blöcher; Roland Frankenberger; Andreas Hellak; Michael Schauseil; Matthias J Roggendorf; Heike Maria Korbmacher-Steiner Journal: BMC Oral Health Date: 2015-03-25 Impact factor: 2.757
Authors: Mary Anne S Melo; Michael D Weir; Vanara F Passos; Juliana P M Rolim; Christopher D Lynch; Lidiany K A Rodrigues; Hockin H K Xu Journal: Int J Mol Sci Date: 2018-11-02 Impact factor: 5.923