| Literature DB >> 2397475 |
T Inaba1, S Murakami, N Oku, K Itoh, Y Ura, S Nakanishi, C Shimazaki, A Nishio, M Nakagawa, N Fujita.
Abstract
Cytogenetic study was performed on a patient with T-cell acute lymphoblastic leukemia (T-ALL). It revealed a chromosomal translocation between chromosome bands 8q24 and 14q11. 8q24 is known to encode the oncogene c-myc, while 14q11 encodes the genes for T-cell receptor-alpha (TCR-alpha) and T-cell receptor-delta (TCR-delta). Therefore, this chromosomal translocation t(8;14) (q24;q11) seemed to be unique and specific to T-cell malignancy.Entities:
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Year: 1990 PMID： 2397475 DOI： 10.1016/0165-4608(90)90165-7
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608