Literature DB >> 2397318

The cognitive effects of alcohol abuse: a controlled study.

C M Williams1, A E Skinner.   

Abstract

It is now well established that there is an association between excessive alcohol consumption and psychological impairment. However, there has been some difficulty in the interpretation of results as the majority of studies have relied on reporting correlations in large subject samples. It was felt therefore that if subjects were matched by variables which had been found to be confounding in previous research, a clearer picture of the effects of alcohol on cognitive functioning could be drawn. Subjects in this study were therefore divided into a 'high' alcohol group (over 50 units per week), and a 'low' alcohol group (under 20 units per week). No patients who had previously been reported as suffering from cognitive impairment were included in this study as the purpose of this research was to examine the effects of alcohol on those heavy drinkers with no obvious impairment. They were matched by age, sex, socio-economic status and educational background. Heavy drinkers showed significant deficits on a number of cognitive tests compared with their matched controls. Furthermore, the subjects in the lower educational group showed a greater decrease in scores on several sub tests than those in the higher group.

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Year:  1990        PMID: 2397318     DOI: 10.1111/j.1360-0443.1990.tb03721.x

Source DB:  PubMed          Journal:  Br J Addict        ISSN: 0952-0481


  2 in total

1.  Effect of ethanol on chromatin and nonhistone nuclear proteins in rat brain.

Authors:  K Mahadev; M C Vemuri
Journal:  Neurochem Res       Date:  1998-09       Impact factor: 3.996

2.  Brain derived neurotrophic factor and cognitive status: the delicate balance among people living with HIV, with and without alcohol abuse.

Authors:  Maria Jose Míguez-Burbano; Luis Espinoza; Nicole Ennis Whitehead; Vaughn E Bryant; Mayra Vargas; Robert L Cook; Clery Quiros; John E Lewis; Asthana Deshratan
Journal:  Curr HIV Res       Date:  2014       Impact factor: 1.581

  2 in total

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