Literature DB >> 23971122

High uptake of Gardasil vaccine among 9 - 12-year-old schoolgirls participating in an HPV vaccination demonstration project in KwaZulu-Natal, South Africa.

I Moodley1, N Tathiah, V Mubaiwa, L Denny.   

Abstract

BACKGROUND: Cervical cancer is linked to infection of the cervix by oncogenic human papillomavirus (HPV) subtypes. The quadrivalent Gardasil vaccine (against HPV types 6, 11, 16, 18), recommended in girls 9 - 12 years of age, has been shown to be safe, immunogenic and efficacious, with minimal or no side-effects. AIM: To demonstrate the capacity of school health teams to carry out vaccinations within a school environment.
OBJECTIVES: To assess the uptake of 3 doses of the vaccine, document lessons learnt and provide recommendations for a national rollout of school-based HPV vaccination for learners.
METHODS: Female learners (age 9 - 12 years) from 31 primary schools in Nongoma and Ceza districts (KwaZulu-Natal province, South Africa) were identified for inclusion in the vaccination programme. The 3 doses of vaccine were administered by existing school health teams. Education and training sessions were held with all stakeholders: provincial departments of health and education; school health teams; primary healthcare nurses; hospital doctors and nurses; private practitioners; school principals, teachers and governing bodies; parents; and community and traditional leaders.
RESULTS: The overall uptake of the vaccine was found to be high: 99.7%, 97.9% and 97.8% for the first, second and third doses respectively (N = 963). No adverse events were attributed to the HPV vaccine.
CONCLUSION: This project demonstrated the successful implementation of HPV vaccination among learners (ages 9 - 12 years) using school health teams.

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Year:  2013        PMID: 23971122     DOI: 10.7196/samj.6414

Source DB:  PubMed          Journal:  S Afr Med J


  29 in total

1.  Knowledge of HPV among HIV-Infected and HIV-Uninfected Adolescent Women in South Africa.

Authors:  David C Griffith; David Adler; Melissa Wallace; Thola Bennie; Beau Abar; Linda-Gail Bekker
Journal:  J Womens Health Issues Care       Date:  2015-09-23

2.  Reporting of adverse events following immunizations in Ghana - Using disproportionality analysis reporting ratios.

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Journal:  Hum Vaccin Immunother       Date:  2017-11-27       Impact factor: 3.452

3.  Factors influencing the recommendation of the Human Papillomavirus vaccine by South African doctors working in a tertiary hospital.

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Journal:  Afr Health Sci       Date:  2016-06       Impact factor: 0.927

Review 4.  Quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine (gardasil(®)): a review of its use in the prevention of premalignant anogenital lesions, cervical and anal cancers, and genital warts.

Authors:  Paul L McCormack
Journal:  Drugs       Date:  2014-07       Impact factor: 11.431

5.  Implementation of an HPV vaccination program in Eldoret, Kenya: results from a qualitative assessment by key stakeholders.

Authors:  Heleen Vermandere; Violet Naanyu; Olivier Degomme; Kristien Michielsen
Journal:  BMC Public Health       Date:  2015-09-10       Impact factor: 3.295

Review 6.  Knowledge and awareness of HPV vaccine and acceptability to vaccinate in sub-Saharan Africa: a systematic review.

Authors:  Stacey Perlman; Richard G Wamai; Paul A Bain; Thomas Welty; Edith Welty; Javier Gordon Ogembo
Journal:  PLoS One       Date:  2014-03-11       Impact factor: 3.240

7.  Determinants of acceptance and subsequent uptake of the HPV vaccine in a cohort in Eldoret, Kenya.

Authors:  Heleen Vermandere; Violet Naanyu; Hillary Mabeya; Davy Vanden Broeck; Kristien Michielsen; Olivier Degomme
Journal:  PLoS One       Date:  2014-10-09       Impact factor: 3.240

8.  Performance of 21 HPV vaccination programs implemented in low and middle-income countries, 2009-2013.

Authors:  Joël Ladner; Marie-Hélène Besson; Mariana Rodrigues; Etienne Audureau; Joseph Saba
Journal:  BMC Public Health       Date:  2014-06-30       Impact factor: 3.295

9.  Knowledge on HPV Vaccine and Cervical Cancer Facilitates Vaccine Acceptability among School Teachers in Kitui County, Kenya.

Authors:  Moses Muia Masika; Javier Gordon Ogembo; Sophie Vusha Chabeda; Richard G Wamai; Nelly Mugo
Journal:  PLoS One       Date:  2015-08-12       Impact factor: 3.240

10.  Knowledge, attitudes and practices on adolescent vaccination among parents, teachers and adolescents in Africa: a systematic review protocol.

Authors:  Leila H Abdullahi; Benjamin M Kagina; Tali Cassidy; Esther F Adebayo; Charles S Wiysonge; Gregory D Hussey
Journal:  Syst Rev       Date:  2014-09-09
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