OBJECTIVE: Over the past two decades, neurobiological studies in adult onset borderline personality disorder have made important strides, but inquiry into adolescent-onset BPD is still in its infancy and our understanding of the neurobiology of adolescent BPD remains highly tentative. METHODS: This paper highlights recent findings in genetics, neuroendocrinology and neuroimaging for adult and adolescent-onset BPD. RESULTS: Neurobiological studies of adolescent-onset BPD to date have focused mainly on volumetric studies of various brain regions and measurements of HPA axis components, with comparatively few publications on brain functioning. CONCLUSION: Such information is essential to developing more effective screening, treatment and preventive strategies.
OBJECTIVE: Over the past two decades, neurobiological studies in adult onset borderline personality disorder have made important strides, but inquiry into adolescent-onset BPD is still in its infancy and our understanding of the neurobiology of adolescent BPD remains highly tentative. METHODS: This paper highlights recent findings in genetics, neuroendocrinology and neuroimaging for adult and adolescent-onset BPD. RESULTS: Neurobiological studies of adolescent-onset BPD to date have focused mainly on volumetric studies of various brain regions and measurements of HPA axis components, with comparatively few publications on brain functioning. CONCLUSION: Such information is essential to developing more effective screening, treatment and preventive strategies.
Authors: J C Pascual; J Soler; M Baiget; A Cortés; A Menoyo; J Barrachina; M Ropero; M Gomà; E Alvarez; V Perez Journal: Actas Esp Psiquiatr Date: 2007 Nov-Dec Impact factor: 1.196
Authors: Nelson H Donegan; Charles A Sanislow; Hilary P Blumberg; Robert K Fulbright; Cheryl Lacadie; Pawel Skudlarski; John C Gore; Ingrid R Olson; Thomas H McGlashan; Bruce E Wexler Journal: Biol Psychiatry Date: 2003-12-01 Impact factor: 13.382
Authors: Peter Fonagy; Mario Speranza; Patrick Luyten; Michael Kaess; Christel Hessels; Martin Bohus Journal: Eur Child Adolesc Psychiatry Date: 2015-08-14 Impact factor: 4.785