Literature DB >> 2397056

DNA amplification of HIV-1 in seropositive individuals and in seronegative at-risk individuals.

M Mariotti1, J J Lefrère, B Noel, F Ferrer-Le-Coeur, D Vittecoq, R Girot, C Bosser, A M Couroucé, C Salmon, P Rouger.   

Abstract

We assessed the HIV-1 status of seropositive and seronegative at-risk individuals by the polymerase chain reaction. Fifty-four out of 55 HIV-1-seropositive samples scored positive. However, HIV-1 proviral DNA was not detected in 16 seronegative homosexuals, 20 seronegative polytransfused haemophiliacs and 20 seronegative thalassaemic children, 20 individuals with isolated and persistent anti-core antibodies and 74 seronegative blood donors. These data indicate that positive HIV-1 DNA is likely to be an exceptional phenomenon in HIV-seronegative people.

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Year:  1990        PMID： 2397056     DOI： 10.1097/00002030-199007000-00004

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  9 in total

1.  Concordance between polymerase chain reaction and antibody detection in the diagnosis of human immunodeficiency virus type 1 infection.

Authors:  L Romano; M Catucci; A De Milito; G Venturi; M Zazzi; P Almi; A Gonnelli; M Rubino; R Maestrini; P E Valensin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1995-11       Impact factor: 3.267

2.  Reactivity patterns and infection status of serum samples with indeterminate Western immunoblot tests for antibody to human immunodeficiency virus type 1.

Authors:  E Ramirez; P Uribe; D Escanilla; G Sanchez; R T Espejo
Journal:  J Clin Microbiol       Date:  1992-04       Impact factor: 5.948

3.  Investigating the presence of HIV sequences and the distribution of virological markers in hemophiliacs and their sexual partners.

Authors:  M da S Cardoso; S Epple; K Koerner; B Kubanek; D Ellbrück; E Seifried
Journal:  Ann Hematol       Date:  1991-12       Impact factor: 3.673

4.  P24 antigen detection, viral isolation, DNA-PCR and in vitro antibody production for the diagnosis of HIV-1 latent infection in heterosexual women at high risk for HIV-1 infection.

Authors:  M Di Stefano; J R Fiore; M Chironna; G Buccoliero; C Romanelli; L La Grasta; M Quarto; G Angarano; G Pastore
Journal:  Genitourin Med       Date:  1995-04

5.  DNA amplification of HIV genome in hemophiliacs and in newborns from seropositive mothers.

Authors:  C de la Salle; M J Baas; D Laustriat; B Guy; E Bordes; M L Wiesel; L Grunebaum; P Lutz; M Partisani; J M Lang
Journal:  Ann Hematol       Date:  1991-05       Impact factor: 3.673

6.  Low human immunodeficiency virus type 1 (HIV-1) DNA burden as a major cause for failure to detect HIV-1 DNA in clinical specimens by PCR.

Authors:  M Zazzi; L Romano; M Catucci; A De Milito; P Almi; A Gonnelli; M Rubino; P E Valensin
Journal:  J Clin Microbiol       Date:  1995-01       Impact factor: 5.948

Review 7.  Pathogenesis of human immunodeficiency virus infection.

Authors:  J A Levy
Journal:  Microbiol Rev       Date:  1993-03

8.  Use of dried blood spot specimens in the detection of human immunodeficiency virus type 1 by the polymerase chain reaction.

Authors:  S Cassol; T Salas; M Arella; P Neumann; M T Schechter; M O'Shaughnessy
Journal:  J Clin Microbiol       Date:  1991-04       Impact factor: 5.948

9.  Human immunodeficiency virus (HIV) nef-specific cytotoxic T lymphocytes in noninfected heterosexual contact of HIV-infected patients.

Authors:  P Langlade-Demoyen; N Ngo-Giang-Huong; F Ferchal; E Oksenhendler
Journal:  J Clin Invest       Date:  1994-03       Impact factor: 14.808
  9 in total

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