Literature DB >> 23969443

Medical research: Trial unpredictability yields predictable therapy gains.

Benjamin Djulbegovic1, Ambuj Kumar, Paul Glasziou, Branko Miladinovic, Iain Chalmers.   

Abstract

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Year:  2013        PMID： 23969443      PMCID： PMC3819120          DOI： 10.1038/500395a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  8 in total

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Journal:  BMJ       Date:  2007-02-17

2.  Articulating and responding to uncertainties in clinical research.

Authors:  Benjamin Djulbegovic
Journal:  J Med Philos       Date:  2007 Mar-Apr

3.  Strong Inference: Certain systematic methods of scientific thinking may produce much more rapid progress than others.

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Journal:  Science       Date:  1964-10-16       Impact factor: 47.728

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5.  What is the prior probability of a proposed new treatment being superior to established treatments?

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6.  Sorting out the doctor's bag.

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Journal:  Control Clin Trials       Date:  1980-12

7.  Treatment success in cancer: industry compared to publicly sponsored randomized controlled trials.

Authors:  Benjamin Djulbegovic; Ambuj Kumar; Branko Miladinovic; Tea Reljic; Sanja Galeb; Asmita Mhaskar; Rahul Mhaskar; Iztok Hozo; Dongsheng Tu; Heather A Stanton; Christopher M Booth; Ralph M Meyer
Journal:  PLoS One       Date:  2013-03-21       Impact factor: 3.240

8.  New treatments compared to established treatments in randomized trials.

Authors:  Benjamin Djulbegovic; Ambuj Kumar; Paul P Glasziou; Rafael Perera; Tea Reljic; Louise Dent; James Raftery; Marit Johansen; Gian Luca Di Tanna; Branko Miladinovic; Heloisa P Soares; Gunn E Vist; Iain Chalmers
Journal:  Cochrane Database Syst Rev       Date:  2012-10-17
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2.  Are outcome-adaptive allocation trials ethical?

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Journal:  Clin Trials       Date:  2015-02-03       Impact factor: 2.486

Review 3.  Is the decision on the use of biosimilar growth hormone based on high quality scientific evidence? - a systematic review.

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Journal:  Eur J Clin Pharmacol       Date:  2014-02-26       Impact factor: 2.953

Review 4.  Efficient design of clinical trials and epidemiological research: is it possible?

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Review 5.  Overcoming obstacles in the design of cancer anorexia/weight loss trials.

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6.  Non-Inferiority Trials in Medicine: Practice Changing or a Self-Fulfilling Prophecy?

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Journal:  J Gen Intern Med       Date:  2018-01       Impact factor: 5.128

7.  Testing many treatments within a single protocol over 10 years at MRC Clinical Trials Unit at UCL: Multi-arm, multi-stage platform, umbrella and basket protocols.

Authors:  Mahesh Kb Parmar; Matthew R Sydes; Fay H Cafferty; Babak Choodari-Oskooei; Ruth E Langley; Louise Brown; Patrick Pj Phillips; Melissa R Spears; Sam Rowley; Richard Kaplan; Nicholas D James; Timothy Maughan; Nicholas Paton; Patrick J Royston
Journal:  Clin Trials       Date:  2017-08-22       Impact factor: 2.486

8.  Most medical practices are not parachutes: a citation analysis of practices felt by biomedical authors to be analogous to parachutes.

Authors:  Michael J Hayes; Victoria Kaestner; Sham Mailankody; Vinay Prasad
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9.  'Optimism bias' in contemporary national clinical trial network phase III trials: are we improving?

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Review 10.  Statistical and Methodological Considerations for the Interpretation of Intranasal Oxytocin Studies.

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