Literature DB >> 239688

Acetyl-Coenzyme A carboxylase. Role of the prosthetic group in enzyme polymerization.

A D Landman, K Darkshinamurti.   

Abstract

Apo-(acetyl-CoA carboxylase) completely free from the holoenzyme was prepared from biotin-deficient rat adipose tissue by using affinity chromatography. The apoenzyme does not aggregate under conditions favouring the transition of the holoenzyme to the polymeric form. Such transition is possible after the conversion of the apoenzyme into the holoenzyme in vitro, thus demonstrating the requirement of the prosthetic biotinyl group for enzyme activation.

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Year:  1975        PMID： 239688      PMCID： PMC1165255          DOI： 10.1042/bj1450545

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  [ON THE BIOSYNTHESIS OF FATTY ACIDS. V. ACETYL-COA CARBOXYLASE FROM RAT LIVER AND ITS ACTIVATION BY CITRIC ACID].

Authors:  M MATSUHASHI; S MATSUHASHI; F LYNEN
Journal:  Biochem Z       Date:  1964-08-11

2.  Studies on the mechnism of activation of acetyl coenzyme A carboxylase by citrate.

Authors:  P R VAGELOS; A W ALBERTS; D B MARTIN
Journal:  J Biol Chem       Date:  1963-02       Impact factor: 5.157

3.  The mechanism of tricarboxylic acid cycle regulation of fatty acid synthesis.

Authors:  D B MARTIN; P R VAGELOS
Journal:  J Biol Chem       Date:  1962-06       Impact factor: 5.157

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Acetyl coenzyme A carboxylase. 3. Further studies on the relation of catalytic activity to polymeric state.

Authors:  J Moss; M D Lane
Journal:  J Biol Chem       Date:  1972-08-25       Impact factor: 5.157

6.  The presence of acetyl-coenzyme A carboxylase apoenzyme in the liver of newly hatched chicks.

Authors:  E Ryder
Journal:  Biochem J       Date:  1972-06       Impact factor: 3.857

7.  Acetyl-CoA holocarboxylase synthetase of rat adipose tissue.

Authors:  P R Desjardins; K Dakshinamurti
Journal:  Can J Biochem       Date:  1971-08

8.  Transcarboxylase. IX. Parameters effecting dissociation and reassociation of the enzyme.

Authors:  B Jacobson; B I Gerwin; F Ahmad; P Waegell; H G Wood
Journal:  J Biol Chem       Date:  1970-12-10       Impact factor: 5.157

9.  Acetyl-CoA holocarboxylase synthesis in biotin-deficient rat adipose tissue.

Authors:  P R Desjardins; K Dakshinamurti
Journal:  Arch Biochem Biophys       Date:  1971-01       Impact factor: 4.013

10.  Lipogenesis in biotin deficiency.

Authors:  K Dakshinamurti; P R Desjardins
Journal:  Can J Biochem       Date:  1968-10
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  2 in total

1.  Activation of immobilized acetyl-Coenzyme A carboxylase.

Authors:  A D Landman; J Lampert
Journal:  Biochem J       Date:  1978-01-01       Impact factor: 3.857

2.  Thyroid hormone responsive protein Spot14 enhances catalysis of fatty acid synthase in lactating mammary epithelium.

Authors:  Michael C Rudolph; Elizabeth A Wellberg; Andrew S Lewis; Kristina L Terrell; Andrea L Merz; N Karl Maluf; Natalie J Serkova; Steven M Anderson
Journal:  J Lipid Res       Date:  2014-04-25       Impact factor: 5.922
  2 in total

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