| Literature DB >> 23966502 |
Francis J Gilchrist1, Hayley Sims, Alice Alcock, Andrew M Jones, Rowland J Bright-Thomas, David Smith, Patrik Španel, A Kevin Webb, Warren Lenney.
Abstract
Biofilm cultures of Burkholderia cepacia complex (BCC) infection have been found to generate the nonvolatile cyanide ion. We investigated if gaseous hydrogen cyanide (HCN) was a marker of BCC infection. Selected ion flow tube mass spectrometry analysis showed HCN was not elevated in the headspace of planktonic or biofilm cultures or in the exhaled breath of adult cystic fibrosis patients with chronic BCC infection. HCN is therefore not an in vitro or in vivo marker of BCC.Entities:
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Year: 2013 PMID: 23966502 PMCID: PMC3889779 DOI: 10.1128/JCM.02157-13
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948