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Literature DB >> 23966458

Low complement levels in paediatric systemic lupus erythematosus and the risk of bacteraemia.

Jaap P Hagen¹, Petra C E Hissink Muller, Robbert G M Bredius, Rebecca ten Cate.

Abstract

This report describes an 11-year-old girl with systemic lupus erythematosus (SLE) with long-standing low levels of complement proteins. A disease period with lupus nephritis (class IIIa) was complicated by Staphylococcus aureus bacteraemia and osteomyelitis. She was treated with high-dose immunosuppressants and 6 weeks of high-dose intravenous antibiotics. The clinician should be aware of bacteraemia in SLE with secondary complement deficiency.

Entities: Disease Species

Mesh：

Substances：

Year: 2013 PMID： 23966458 PMCID： PMC3762216 DOI： 10.1136/bcr-2013-010378

Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X

15 in total

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Authors: M C Pickering; M Botto; P R Taylor; P J Lachmann; M J Walport
Journal: Adv Immunol Date: 2000 Impact factor: 3.543

Review 2. Systemic lupus erythematosus.

Authors: George C Tsokos
Journal: N Engl J Med Date: 2011-12-01 Impact factor: 91.245

3. Epidemiology and clinical outcomes of bloodstream infections among lupus patients.

Authors: M Marcos; C Fernández; A Soriano; F Marco; J A Martínez; M Almela; R Cervera; J Mensa; G Espinosa
Journal: Lupus Date: 2011-06-09 Impact factor: 2.911

Review 4. Complement deficiency states and associated infections.

Authors: Lillemor Skattum; Marcel van Deuren; Tom van der Poll; Lennart Truedsson
Journal: Mol Immunol Date: 2011-05-31 Impact factor: 4.407

5. Infections in systemic lupus erythematosus: a prospective and controlled study of 110 patients.

Authors: X Bosch; A Guilabert; L Pallarés; R Cerveral; M Ramos-Casals; A Bové; M Ingelmo; J Font
Journal: Lupus Date: 2006 Impact factor: 2.911

6. Long-term outcome and short-term survival of patients with systemic lupus erythematosus after bacteraemia episodes: 6-yr follow-up.

Authors: M-J Chen; H-M Tseng; Y-L Huang; W-N Hsu; K-W Yeh; T-L Wu; L-C See; J-L Huang
Journal: Rheumatology (Oxford) Date: 2008-06-19 Impact factor: 7.580

Low complement levels in paediatric systemic lupus erythematosus and the risk of bacteraemia.

Review 1. Systemic lupus erythematosus, complement deficiency, and apoptosis.

Review 2. Systemic lupus erythematosus.

3. Epidemiology and clinical outcomes of bloodstream infections among lupus patients.

Review 4. Complement deficiency states and associated infections.

5. Infections in systemic lupus erythematosus: a prospective and controlled study of 110 patients.

6. Long-term outcome and short-term survival of patients with systemic lupus erythematosus after bacteraemia episodes: 6-yr follow-up.

7. The 1982 revised criteria for the classification of systemic lupus erythematosus.

Review 8. Complement deficiencies and systemic lupus erythematosus.

Review 9. The role of complement in the development of systemic lupus erythematosus.

10. Anti-C1q antibodies antedate patent active glomerulonephritis in patients with systemic lupus erythematosus.

1. Complement C4 induces regulatory T cells differentiation through dendritic cell in systemic lupus erythematosus.