Literature DB >> 23965606

Effective treatment of catatonia by combination of benzodiazepine and electroconvulsive therapy.

Ahmet Unal1, Feridun Bulbul, Gokay Alpak, Osman Virit, U Sertan Copoglu, Haluk A Savas.   

Abstract

OBJECTIVE: Catatonia, a motor dysregulation syndrome, can emerge in numerous psychiatric disorders, mainly in schizophrenia and mood disorders, and metabolic and endocrine disorders such as infections, toxic states, epilepsy, and traumatic brain injury. In our study, we aimed to investigate demographic, clinical, and treatment-related characteristics of catatonic patients managed in our inpatient clinic.
METHODS: The medical records of 57 patients diagnosed to have catatonia according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, criteria who were admitted to the inpatient psychiatry clinic of the Gaziantep University School of Medicine between 1 January, 2003, and 31 December, 2011, were retrospectively reviewed.
RESULTS: In patients with catatonia, mood disorders (63.2%) were found to be the most common underlying or primary disease, whereas mutism (47.4%) was found to be the most common catatonic symptom. There was a comorbid medical condition in 9 patients (15.8%). Patients underwent an average of 9.00 electroconvulsive therapy (ECT) sessions. Among 57 patients with catatonia, catatonic symptoms were resolved in 57 patients (100%) by benzodiazepine and ECT.
CONCLUSIONS: In our study, full recovery was achieved in catatonia by benzodiazepine plus ECT combination. As a result, we recommend combined ECT and benzodiazepine for catatonia.

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Year:  2013        PMID: 23965606     DOI: 10.1097/YCT.0b013e3182887a1a

Source DB:  PubMed          Journal:  J ECT        ISSN: 1095-0680            Impact factor:   3.635


  7 in total

Review 1.  Is electroconvulsive therapy an evidence-based treatment for catatonia? A systematic review and meta-analysis.

Authors:  Arnaud Leroy; Florian Naudet; Guillaume Vaiva; Andrew Francis; Pierre Thomas; Ali Amad
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2017-06-21       Impact factor: 5.270

Review 2.  Electroconvulsive therapy in catatonic patients: Efficacy and predictors of response.

Authors:  Federica Luchini; Pierpaolo Medda; Michela Giorgi Mariani; Mauro Mauri; Cristina Toni; Giulio Perugi
Journal:  World J Psychiatry       Date:  2015-06-22

Review 3.  Melancholia and catatonia: disorders or specifiers?

Authors:  Gordon Parker; Georgia McClure; Amelia Paterson
Journal:  Curr Psychiatry Rep       Date:  2015-01       Impact factor: 5.285

4.  Impact of High Dose Lorazepam on Seizure Threshold in Catatonia: Experience from a Case Study.

Authors:  Sujita Kumar Kar; Saurabh Kumar; Amit Singh
Journal:  Clin Psychopharmacol Neurosci       Date:  2016-08-31       Impact factor: 2.582

Review 5.  Systematic review of catatonia treatment.

Authors:  Anne Cm Pelzer; Frank Mma van der Heijden; Erik den Boer
Journal:  Neuropsychiatr Dis Treat       Date:  2018-01-17       Impact factor: 2.570

6.  The Role of Electroconvulsive Therapy (ECT) in Bipolar Disorder: Effectiveness in 522 Patients with Bipolar Depression, Mixed-state, Mania and Catatonic Features.

Authors:  Giulio Perugi; Pierpaolo Medda; Cristina Toni; Michela Giorgi Mariani; Chiara Socci; Mauro Mauri
Journal:  Curr Neuropharmacol       Date:  2017-04       Impact factor: 7.363

Review 7.  Catatonia in autism spectrum disorders: A systematic review and meta-analysis.

Authors:  J Vaquerizo-Serrano; G Salazar De Pablo; J Singh; P Santosh
Journal:  Eur Psychiatry       Date:  2021-12-15       Impact factor: 5.361

  7 in total

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