Literature DB >> 23964049

Novel psychoactive substances: a novel clinical challenge.

Christopher Daniel Smith1, Margaret Williams, Maliha Shaikh.   

Abstract

The recreational use of novel psychoactive substances in the UK has increased markedly within the last decade. The variety of new substances synthesised and sold as 'legal', often under the pretence of being 'plant food' or 'bath salts' is similarly increasing. This presents challenges to clinicians: they may be unaware of these substances or unable to identify them and their potential for complications and drug interactions. This case describes a patient who ingested a novel psychoactive substance and presented with severe agitation following a delay of several days. He experienced renal, hepatic and neurological complications requiring critical care input. Our case adds to the current repertoire of knowledge regarding the effects of ingestion of novel cathinones.

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Substances:

Year:  2013        PMID: 23964049      PMCID: PMC3762549          DOI: 10.1136/bcr-2013-200663

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  2 in total

1.  Hyperthermia and multiorgan failure after abuse of "bath salts" containing 3,4-methylenedioxypyrovalerone.

Authors:  Heather A Borek; Christopher P Holstege
Journal:  Ann Emerg Med       Date:  2012-03-03       Impact factor: 5.721

Review 2.  The toxicology of bath salts: a review of synthetic cathinones.

Authors:  Jane M Prosser; Lewis S Nelson
Journal:  J Med Toxicol       Date:  2012-03
  2 in total
  5 in total

1.  Novel psychoactive substances: overdose of 3-fluorophenmetrazine (3-FPM) and etizolam in a 33-year-old man.

Authors:  Matthew G K Benesch; Sahar J Iqbal
Journal:  BMJ Case Rep       Date:  2018-06-08

2.  A novel psychoactive substance poses a new challenge in the management of paranoid schizophrenia.

Authors:  Caroline Anderson; Christopher Morrell; David Marchevsky
Journal:  BMJ Case Rep       Date:  2015-05-06

3.  Synthetic psychoactive cathinones: hypothermia and reduced lethality compared to methamphetamine and methylenedioxymethamphetamine.

Authors:  Dawn E Muskiewicz; Federico Resendiz-Gutierrez; Omar Issa; F Scott Hall
Journal:  Pharmacol Biochem Behav       Date:  2020-02-12       Impact factor: 3.533

4.  Can Google Searches Predict the Popularity and Harm of Psychoactive Agents?

Authors:  Wojciech Jankowski; Marcin Hoffmann
Journal:  J Med Internet Res       Date:  2016-02-25       Impact factor: 5.428

Review 5.  Systematic review of nephrotoxicity of drugs of abuse, 2005-2016.

Authors:  Kanaan Mansoor; Murad Kheetan; Saba Shahnawaz; Anna P Shapiro; Eva Patton-Tackett; Larry Dial; Gary Rankin; Prasanna Santhanam; Antonios H Tzamaloukas; Tibor Nadasdy; Joseph I Shapiro; Zeid J Khitan
Journal:  BMC Nephrol       Date:  2017-12-29       Impact factor: 2.388

  5 in total

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