Literature DB >> 2396349

Analysis of serum placental alkaline phosphatase activity in testicular cancer and cigarette smokers.

K Koshida1, T Stigbrand, E Munck-Wikland, H Hisazumi, B Wahren.   

Abstract

Serum PLAP/PLAP-like enzymes are elevated in testicular cancer patients and also in heavy smokers. Such elevations were measurable with anti-PLAP polyclonal and monoclonal antibodies, and an antigenic heterogeneity was demonstrated in the circulating enzymes. Thus polyclonal antibody revealed more of tumor PLAP-like antigen while a monoclonal antibody H7 detected PLAP of smokers better. PLAP of smokers and PLAP-like enzyme of cancer (seminoma) patients showed similar characteristics with respect to glycosylation pattern, charge and hydrophobicity. By these properties they were differentiated from PLAP of placenta.

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Year:  1990        PMID： 2396349     DOI： 10.1007/bf00295842

Source DB:  PubMed          Journal:  Urol Res        ISSN： 0300-5623


  18 in total

1.  Patterns of seminoma tissue markers and deletions.

Authors:  H Yamamoto; U Rudén; E Ljungdahl-Ståhle; E Brehmer-Andersson; K Hirano; H Hisazumi; T Stigbrand; B Wahren
Journal:  Int J Cancer       Date:  1987-11-15       Impact factor: 7.396

2.  Hydrophobicity and lectin affinity of alkaline phosphatase isozymes in seminoma and normal testis.

Authors:  K Koshida; T Stigbrand; H Hisazumi; B Wahren
Journal:  Tumour Biol       Date:  1989

3.  Increased carcinoembryonic antigen in heavy cigarette smokers.

Authors:  D P Stevens; I R Mackay
Journal:  Lancet       Date:  1973-12-01       Impact factor: 79.321

4.  Penetration of the respiratory epithelium of guinea pigs following exposure to cigarette smoke.

Authors:  A S Simani; S Inoue; J C Hogg
Journal:  Lab Invest       Date:  1974-07       Impact factor: 5.662

5.  Demonstration of placental and placental-like alkaline phosphatase in non-malignant human tissue extracts using monoclonal antibodies in an enzyme immunoassay.

Authors:  P J McLaughlin; P J Travers; I W McDicken; P M Johnson
Journal:  Clin Chim Acta       Date:  1984-03-13       Impact factor: 3.786

6.  Chronic air-flow limitation does not increase respiratory epithelial permeability assessed by aerosolized solute, but smoking does.

Authors:  G J Huchon; J A Russell; L G Barritault; A Lipavsky; J F Murray
Journal:  Am Rev Respir Dis       Date:  1984-09

7.  Effect of age and cigarette smoking on carcinoembryonic antigen levels.

Authors:  J C Alexander; N A Silverman; P B Chretien
Journal:  JAMA       Date:  1976-05-03       Impact factor: 56.272

8.  A search for trace expression of placental-like alkaline phosphatase in non-malignant human tissues: demonstration of its occurrence in lung, cervix, testis and thymus.

Authors:  D J Goldstein; C Rogers; H Harris
Journal:  Clin Chim Acta       Date:  1982-10-13       Impact factor: 3.786

9.  Eutopic expression of placental-like alkaline phosphatase in testicular tumors.

Authors:  A Jeppsson; B Wahren; E Brehmer-Andersson; C Silfverswärd; T Stigbrand; J L Millán
Journal:  Int J Cancer       Date:  1984-12-15       Impact factor: 7.396

10.  Monoclonal antibody assay of serum placental alkaline phosphatase in the monitoring of testicular tumours.

Authors:  A A Epenetos; A J Munro; D F Tucker; W Gregory; W Duncan; R H MacDougall; M Faux; P Travers; W F Bodmer
Journal:  Br J Cancer       Date:  1985-05       Impact factor: 7.640
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  5 in total

1.  Differences in tumor-associated protein levels among middle-age Flemish women in association with area of residence and exposure to pollutants.

Authors:  Nicolas A van Larebeke; Marc E Bracke; Vera Nelen; Gudrun Koppen; Greet Schoeters; Herman Van Loon; Robert Vlietinck
Journal:  Environ Health Perspect       Date:  2006-06       Impact factor: 9.031

2.  Pollutant effects on genotoxic parameters and tumor-associated protein levels in adults: a cross sectional study.

Authors:  Sam De Coster; Gudrun Koppen; Marc Bracke; Carmen Schroijen; Elly Den Hond; Vera Nelen; Els Van de Mieroop; Liesbeth Bruckers; Maaike Bilau; Willy Baeyens; Greet Schoeters; Nik van Larebeke
Journal:  Environ Health       Date:  2008-06-03       Impact factor: 5.984

3.  DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk.

Authors:  Laura Baglietto; Erica Ponzi; Philip Haycock; Allison Hodge; Manuela Bianca Assumma; Chol-Hee Jung; Jessica Chung; Francesca Fasanelli; Florence Guida; Gianluca Campanella; Marc Chadeau-Hyam; Kjell Grankvist; Mikael Johansson; Ugo Ala; Paolo Provero; Ee Ming Wong; Jihoon Joo; Dallas R English; Nabila Kazmi; Eiliv Lund; Christian Faltus; Rudolf Kaaks; Angela Risch; Myrto Barrdahl; Torkjel M Sandanger; Melissa C Southey; Graham G Giles; Mattias Johansson; Paolo Vineis; Silvia Polidoro; Caroline L Relton; Gianluca Severi
Journal:  Int J Cancer       Date:  2016-10-11       Impact factor: 7.396

4.  Tobacco smoking leads to extensive genome-wide changes in DNA methylation.

Authors:  Sonja Zeilinger; Brigitte Kühnel; Norman Klopp; Hansjörg Baurecht; Anja Kleinschmidt; Christian Gieger; Stephan Weidinger; Eva Lattka; Jerzy Adamski; Annette Peters; Konstantin Strauch; Melanie Waldenberger; Thomas Illig
Journal:  PLoS One       Date:  2013-05-17       Impact factor: 3.240

5.  Specific immunoassays for placental alkaline phosphatase as a tumor marker.

Authors:  Sérvio T Stinghen; Juliana F Moura; Patrícia Zancanella; Giovanna A Rodrigues; Mara A Pianovski; Enzo Lalli; Dodie L Arnold; João C Minozzo; Luis G Callefe; Raul C Ribeiro; Bonald C Figueiredo
Journal:  J Biomed Biotechnol       Date:  2006
  5 in total

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