Literature DB >> 23963344

Reconstruction of skin avulsion injuries of the upper extremity with integra(®) dermal regeneration template and skin grafts in a single-stage procedure.

Efterpi Demiri1, Antonios Papaconstantinou, Dimitrios Dionyssiou, Alexandros Dionyssopoulos, Katerina Kaidoglou, Ioannis Efstratiou.   

Abstract

INTRODUCTION: Management of skin avulsion injuries of the upper extremity may require coverage with large flaps or skin autografts. Cutaneous grafting is frequently combined with artificial skin to optimize the final functional and cosmetic result. The conventional use of bilaminated dermal substitutes consists of a two-stage procedure and requires long immobilization of the operated area. The purpose of this retrospective study is to evaluate the impact of a dermal regeneration template immediately covered by skin grafts in a one-step procedure for reconstructing skin avulsion injuries of the hand and forearm.
MATERIALS AND METHODS: We performed this technique in eight patients who presented with extended skin defects of the hand and forearm following skin avulsion injuries. Dimensions of the defects ranged from 160 to 1,250 cm(2). After debridement, Integra(®) Single Layer was applied and covered with unmeshed thin skin autografts; compressive dressings were used for 1 week and mobilization started by the second postoperative week. Histological examination of the grafted areas was performed 2 weeks after surgery. Functional and cosmetic outcome was assessed 12 months postoperatively.
RESULTS: The overall take rate of the dermal substitute and skin graft was 95-98 %. Histological results showed complete incorporation and vascular proliferation of the template, which allowed the neo-vascularization of the overlying autograft. The mean grip strength of the operated hands was at the 83 % of the normal contralateral hands. Pliability and overall appearance of the reconstructed areas was satisfactory (mean Vancouver Scar Scale Score 1.875).
CONCLUSIONS: The use of Integra(®) Single Layer dermal substitute and immediate skin overgrafting consists an alternative reconstructive option for managing extended skin avulsion injuries of the upper extremity; it reduces postoperative immobilization, minimizes donor site morbidity and provides good functional and esthetic results in a single surgical procedure.

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Year:  2013        PMID: 23963344     DOI: 10.1007/s00402-013-1834-2

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN: 0936-8051            Impact factor:   3.067


  12 in total

1.  Auricular Total Reconstruction with Radial Forearm Prelaminated Flap Assisted by 3D Surface Imaging and 3D Printing.

Authors:  Marco Aurelio Rendón-Medina; Erik Hanson-Viana; Leidy Arias-Salazar; Jorge Arturo Rojas-Ortiz; Maria de Los Angeles Mendoza-Velez; Rubén Hernandez-Ordoñez; Hecly Lya Vázquez-Morales; Ricardo C Pacheco-López
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-10-13

2.  Nonmicrosurgical options for soft tissue reconstruction of the hand.

Authors:  Jun Matsui; Samantha Piper; Martin I Boyer
Journal:  Curr Rev Musculoskelet Med       Date:  2014-03

3.  Long-term follow-up of donor site morbidity after defect coverage with Integra following radial forearm flap elevation.

Authors:  Anna Wirthmann; Juliane C Finke; Pietro Giovanoli; Nicole Lindenblatt
Journal:  Eur J Plast Surg       Date:  2014-01-10

4.  Comparison between Conventional Mechanical Fixation and Use of Autologous Platelet Rich Plasma (PRP) in Wound Beds Prior to Resurfacing with Split Thickness Skin Graft.

Authors:  Veena P Waiker; Shanthakumar Shivalingappa
Journal:  World J Plast Surg       Date:  2015-01

5.  Revision surgery with dermal regeneration template and vacuum sealing drainage for reconstruction of complex wounds following necrosis of reattached avulsed skins in a degloving injury: A case report.

Authors:  Zhenmu Lv; Lili Yu; Lei Fu; Qiusheng Wang; Rui Jia; Wenyuan Ding; Yong Shen
Journal:  Medicine (Baltimore)       Date:  2019-06       Impact factor: 1.817

6.  Single-stage Composite Skin Reconstruction Using a Dermal Regeneration Template.

Authors:  Pamela A Rudnicki; Boonyapa Purt; Daniel True; Hector Siordia; Steven Lohmeier; Rodney K Chan
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-02-24

7.  Selection of Artificial Dermis for Shortening Treatment Period: Integra versus Pelnac.

Authors:  Tsutomu Kashimura; Keito Nagasaki; Michio Horigome; Kotoku Yoshida; Kazutaka Soejima
Journal:  Plast Reconstr Surg Glob Open       Date:  2021-06-10

8.  Evaluation of Acellular Dermal Matrix (ADM) as a Scaffold for Adipose-Derived Stem Cell Transfer in the Rat Model.

Authors:  Maryam Jahanian; Sara Hoseini; Amir Atashi; Mohsen Saberi; Seyyed Aboozar Hoseini; Kambiz Mozaffari; Mohammad Javad Fatemi
Journal:  World J Plast Surg       Date:  2021-05

9.  Single-Stage Dermal Matrix and Skin Grafting to Treat a Complicated Hand Wound.

Authors:  Mitchell Lyons; Alexis L Parcells; Mark S Granick
Journal:  Eplasty       Date:  2016-06-01

10.  Repeated reverse sural fasciocutaneous flap is an effective surgical strategy for repairing long segmental soft tissue defects of the tibia.

Authors:  Zelong Cui; Xuemei Zhang; Jiabao Shou; Guoqian Yin
Journal:  J Int Med Res       Date:  2019-09-17       Impact factor: 1.671

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