Literature DB >> 2396310

Determination of pentamidine in whole blood, plasma, and urine by high-performance liquid chromatography.

O Ericsson1, M Rais.   

Abstract

The analysis of pentamidine in whole blood, plasma, and urine by liquid chromatography is described. Extraction was made with a mixture of acetonitrile and chloroform followed by back-extraction into phosphate buffer. A reversed-phase chromatographic system with fluorescence detection was used. The precision of the method was 5-7% at the lower limit of determination (16 nmol/L in plasma and hemolyzed whole blood, 27.7 nmol/L in urine).

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Year:  1990        PMID: 2396310     DOI: 10.1097/00007691-199007000-00011

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN: 0163-4356            Impact factor:   3.681


  2 in total

Review 1.  Problems and pitfalls in the assay of pentamidine. Implications for clinical use.

Authors:  B J Berger; L Henry; J E Hall; R R Tidwell
Journal:  Clin Pharmacokinet       Date:  1992-03       Impact factor: 6.447

2.  Pharmacokinetics and adverse reactions after a single dose of pentamidine in patients with Trypanosoma gambiense sleeping sickness.

Authors:  U Bronner; L L Gustafsson; F Doua; O Ericsson; T Miézan; M Rais; L Rombo
Journal:  Br J Clin Pharmacol       Date:  1995-03       Impact factor: 4.335

  2 in total

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