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Literature DB >> 23962399

A novel and other bioactive secondary metabolites from a marine fungus Penicillium oxalicum 0312F1.

Abstract

A new compound 2-(4-hydroxybenzoyl) quinazolin-4(3H)-one (1) and four known compounds were isolated from a marine fungus Penicillium oxalicum 0312F1. The structure of the new compound 1 was elucidated based on the spectroscopic analysis. Bioactivity assays showed that 2-(4-hydroxybenzyl) quinazolin-4(3H)-one (2) and methyl 4-hydroxyphenylacetate (5) had potent inhibitory activity against tobacco mosaic virus (TMV), and the new compound 1 had moderate inhibitory activity against TMV and human gastric cancer cell SGC-7901.

Entities: Chemical Disease Species

Mesh：

Substances：
Antiviral Agents

Year: 2013 PMID： 23962399 DOI： 10.1080/14786419.2013.827190

Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861

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Cited

7 in total

1. Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

Authors: J Houbraken; S Kocsubé; C M Visagie; N Yilmaz; X-C Wang; M Meijer; B Kraak; V Hubka; K Bensch; R A Samson; J C Frisvad
Journal: Stud Mycol Date: 2020-06-27 Impact factor: 16.097

2. Anti-neuroinflammatory effect of oxaline, isorhodoptilometrin, and 5-hydroxy-7-(2'-hydroxypropyl)-2-methyl-chromone obtained from the marine fungal strain Penicillium oxalicum CLC-MF05.

Authors: Dong-Cheol Kim; Tran Hong Quang; Nguyen Thuy Tien; Kwan-Woo Kim; Youn-Chul Kim; Nguyen Thi Thanh Ngan; Nguyen Xuan Cuong; Nguyen Hoai Nam; Hyuncheol Oh
Journal: Arch Pharm Res Date: 2022-01-30 Impact factor: 4.946

3. Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (M^pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis.

Authors: Ibrahim S Uras; Michal Korinek; Amgad Albohy; Basma S Abdulrazik; Wenhan Lin; Sherif S Ebada; Belma Konuklugil
Journal: ChemistrySelect Date: 2022-03-28 Impact factor: 2.307

A novel and other bioactive secondary metabolites from a marine fungus Penicillium oxalicum 0312F1.

1. Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

2. Anti-neuroinflammatory effect of oxaline, isorhodoptilometrin, and 5-hydroxy-7-(2'-hydroxypropyl)-2-methyl-chromone obtained from the marine fungal strain Penicillium oxalicum CLC-MF05.

3. Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (M^pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis.

Review 4. Potential Antiviral Agents from Marine Fungi: An Overview.

Review 5. Potential of small-molecule fungal metabolites in antiviral chemotherapy.

Review 6. Marine-Derived Penicillium Species as Producers of Cytotoxic Metabolites.

7. New Isoxazolidine-Conjugates of Quinazolinones-Synthesis, Antiviral and Cytostatic Activity.

A novel and other bioactive secondary metabolites from a marine fungus Penicillium oxalicum 0312F1.

1. Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

2. Anti-neuroinflammatory effect of oxaline, isorhodoptilometrin, and 5-hydroxy-7-(2'-hydroxypropyl)-2-methyl-chromone obtained from the marine fungal strain Penicillium oxalicum CLC-MF05.

3. Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (Mpro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis.

Review 4. Potential Antiviral Agents from Marine Fungi: An Overview.

Review 5. Potential of small-molecule fungal metabolites in antiviral chemotherapy.

Review 6. Marine-Derived Penicillium Species as Producers of Cytotoxic Metabolites.

7. New Isoxazolidine-Conjugates of Quinazolinones-Synthesis, Antiviral and Cytostatic Activity.

3. Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (M^pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis.