| Literature DB >> 23962140 |
Botros R Michael1, Sahar R Gedara, Mohamed M A Amer, Lesley Stevenson, Atallah F Ahmed.
Abstract
A new highly oxygenated pseudoguaianolide, rudbeckolide (1), was isolated from Rudbeckia hirta L. flowers. The structure of this terpenoid lactone was established on the basis of extensive 1D and 2D NMR spectroscopic analyses. The compound exhibited strong 5-lipoxygenase inhibitory activity (84.9% inhibition at 10 μg/mL) in vitro and the result provided partial evidence for the usage of the plant as traditional medicine.Entities:
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Year: 2013 PMID： 23962140 DOI： 10.1080/14786419.2013.825916
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861