Literature DB >> 23961031

Papilledema and optic disc pit: The association of two pathologies in one patient.

Alberto Galvez-Ruiz1, Nicola Ghazi, Yasir Ruhaily.   

Abstract

Histologically, optic disc pit (ODP) is described as a small congenital defect in the cribriform plate where a herniation of the dysplastic retina extends to the subarachnoid space in the optic nerve, which is surrounded by a layer of collagen-rich tissue. Approximately 25-75% of cases are complicated by optic disc pit maculopathy (ODPM). The pathogenesis of maculopathies associated with ODP has not been fully elucidated. We present an unusual case of a patient with a history of papilledema secondary to a fronto-temporal meningioma. The patient underwent a successful surgical intervention with resolution of the papilledema 15 years before the detection of an ODP that was associated with retinal detachment in the macular region. Several studies have reported on the importance of intracranial pressure in the development of maculopathies associated with ODP. During the period of intracranial hypertension and papilledema in our patient, the hernia sac that was associated with ODP may have been small, which would have decreased the chances of developing a maculopathy that was associated with OPD.

Entities:  

Keywords:  Meningioma; Optic disc pit; Optic disc pit maculopathy; Papilledema

Year:  2012        PMID: 23961031      PMCID: PMC3729635          DOI: 10.1016/j.sjopt.2012.08.004

Source DB:  PubMed          Journal:  Saudi J Ophthalmol        ISSN: 1319-4534


  9 in total

Review 1.  Optic disc pit: a review.

Authors:  Ilias Georgalas; Ioannis Ladas; Gerasimos Georgopoulos; Petros Petrou
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-06-03       Impact factor: 3.117

2.  Intracranial migration of silicone oil from an eye with optic pit.

Authors:  Ferenc Kuhn; Ferenc Kover; Ilona Szabo; Viktoria Mester
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-03-08       Impact factor: 3.117

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Journal:  Arch Ophthalmol       Date:  1988-01

4.  Pathogenic implications of subretinal gas migration through pits and atypical colobomas of the optic nerve.

Authors:  T Mark Johnson; Mark W Johnson
Journal:  Arch Ophthalmol       Date:  2004-12

5.  High-resolution optical coherence tomography findings in optic pit maculopathy.

Authors:  Yutaka Imamura; Sandrine A Zweifel; Takamitsu Fujiwara; K Bailey Freund; Richard F Spaide
Journal:  Retina       Date:  2010 Jul-Aug       Impact factor: 4.256

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Authors:  A R Irvine; J B Crawford; J H Sullivan
Journal:  Retina       Date:  1986 Summer-Fall       Impact factor: 4.256

7.  Optic nerve pit during papilledema.

Authors:  B S Grimson; J D Mann; J P Pantell
Journal:  Arch Ophthalmol       Date:  1982-01

8.  Congenital pits of the optic nerve head. I. Experimental studies in collie dogs.

Authors:  G C Brown; J A Shields; B E Patty; R E Goldberg
Journal:  Arch Ophthalmol       Date:  1979-07

9.  Treatment of total retinal detachment in morning glory syndrome.

Authors:  S Chang; B G Haik; R M Ellsworth; L St Louis; J A Berrocal
Journal:  Am J Ophthalmol       Date:  1984-05       Impact factor: 5.258

  9 in total

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