BACKGROUND AND OBJECTIVES: Accidental and intentional poisonings or drug overdoses constitute a significant source of aggregate morbidity, mortality, and health care expenditure. Studies evaluating drug related hospitalization have estimated that approximately 5-10% of all hospital admissions are drug related. The present study was carried out to investigate type, nature and incidence of drug related admissions in our hospital settings. METHOD: A hospital based retrospective study was conducted in 575 cases of drug related admissions. The case records of patients admitted in various clinical departments of Amrita Institute of Medical Sciences (AIMS) Hospital during last 8 years (January 2002-December 2009) were collected and analyzed. RESULTS: During the retrospective study, the total number of drug related cases reported were 575. Out of these, 35.5% cases were induced by central nervous system (CNS) drugs, 19.8% were by cardiovascular system (CVS) drugs, 12.3% were by NSAIDs, 11.3% were by antibiotics and 9.9% were by anticoagulants, 11.3% by other drugs which includes hormones, cytotoxic drugs, hypolipidemics, etc. Four hundred and forty cases were admitted to emergency department. Common drug related problems resulting in hospital visits were due to intentional, accidental and overdose. The incidence of drug related hospital admissions was found to be 0.20%. CONCLUSION: The most of the accidental and suicidal cases were reported are by CNS drugs. Psychiatric patients intentionally taking medicines as suicidal attempt and as a part of their illness. As drug related problems are so significant, increased awareness and enhanced collaborative efforts among patients, physicians, pharmacists and caregivers within community and hospital have the potential to minimize the impact of this problem.
BACKGROUND AND OBJECTIVES: Accidental and intentional poisonings or drug overdoses constitute a significant source of aggregate morbidity, mortality, and health care expenditure. Studies evaluating drug related hospitalization have estimated that approximately 5-10% of all hospital admissions are drug related. The present study was carried out to investigate type, nature and incidence of drug related admissions in our hospital settings. METHOD: A hospital based retrospective study was conducted in 575 cases of drug related admissions. The case records of patients admitted in various clinical departments of Amrita Institute of Medical Sciences (AIMS) Hospital during last 8 years (January 2002-December 2009) were collected and analyzed. RESULTS: During the retrospective study, the total number of drug related cases reported were 575. Out of these, 35.5% cases were induced by central nervous system (CNS) drugs, 19.8% were by cardiovascular system (CVS) drugs, 12.3% were by NSAIDs, 11.3% were by antibiotics and 9.9% were by anticoagulants, 11.3% by other drugs which includes hormones, cytotoxic drugs, hypolipidemics, etc. Four hundred and forty cases were admitted to emergency department. Common drug related problems resulting in hospital visits were due to intentional, accidental and overdose. The incidence of drug related hospital admissions was found to be 0.20%. CONCLUSION: The most of the accidental and suicidal cases were reported are by CNS drugs. Psychiatricpatients intentionally taking medicines as suicidal attempt and as a part of their illness. As drug related problems are so significant, increased awareness and enhanced collaborative efforts among patients, physicians, pharmacists and caregivers within community and hospital have the potential to minimize the impact of this problem.
Entities:
Keywords:
Drug related problem; Hospital admission; Over dose; Poisoning
Authors: Abubakar Ibrahim Jatau; Myat Moe Thwe Aung; Tuan Hairulnizam Tuan Kamauzaman; Ab Fatah Ab Rahman Journal: Drugs Real World Outcomes Date: 2015-10-23
Authors: Mulugeta Tarekegn Angamo; Colin Michael Curtain; Leanne Chalmers; Daniel Yilma; Luke Bereznicki Journal: PLoS One Date: 2017-10-16 Impact factor: 3.240
Authors: João Paulo Vilela Rodrigues; Fabiana Angelo Marques; Ana Maria Rosa Freato Gonçalves; Marília Silveira de Almeida Campos; Tiago Marques Dos Reis; Manuela Roque Siani Morelo; Andrea Fontoura; Beatriz Maria Pereira Girolineto; Helen Palmira Miranda de Camargo Souza; Maurílio de Souza Cazarim; Lauro César da Silva Maduro; Leonardo Régis Leira Pereira Journal: PLoS One Date: 2019-01-18 Impact factor: 3.240