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Literature DB >> 23959809

HLA in Georgians (Caucasus) and their relationship with Eastern Mediterraneans.

Diego Rey, Cristina Areces, Javier Alonso-Rubio, Mercedes Enríquez-de-Salamanca, Sedeka Abd-El-Fatah-Khalil, Nina Bendikuze, Mercedes Fernández-Honrado, Luz Barbolla, José Manuel Martín-Villa, Antonio Arnaiz-Villena.

Abstract

HLA-A, -B, -DQB1, and -DRB1 typing has been performed in a sample of Georgian population (South Caucasus). Allele frequencies, neighbour joining and correspondence relatedness analyses and extended HLA haplotypes have been obtained with comparison with other Middle East and Mediterranean populations. Our Georgian sample tends to be genetically related in these analyses with Eastern Mediterraneans and Middle East people. This is important for future regional transplant programs, and Georgian HLA and disease epidemiology and pharmacogenomics.

Entities: Gene Species

Mesh：

Substances：

Year: 2013 PMID： 23959809 DOI： 10.1007/s11033-013-2651-y

Source DB: PubMed Journal: Mol Biol Rep ISSN： 0301-4851 Impact factor: 2.316

29 in total

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Journal: Tissue Antigens Date: 2000-03

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Journal: Science Date: 1982-12-03 Impact factor: 47.728

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Journal: Hum Immunol Date: 2000-06 Impact factor: 2.850

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Authors: N Saitou; M Nei
Journal: Mol Biol Evol Date: 1987-07 Impact factor: 16.240

5. HLA allele and haplotype frequencies in Algerians. Relatedness to Spaniards and Basques.

Authors: A Arnaiz-Villena; D Benmamar; M Alvarez; N Diaz-Campos; P Varela; E Gomez-Casado; J Martinez-Laso
Journal: Hum Immunol Date: 1995-08 Impact factor: 2.850

6. Accuracy of estimated phylogenetic trees from molecular data. II. Gene frequency data.

Authors: M Nei; F Tajima; Y Tateno
Journal: J Mol Evol Date: 1983 Impact factor: 2.395

7. Brief report: primary immunodeficiency caused by mutations in the gene encoding the CD3-gamma subunit of the T-lymphocyte receptor.

Authors: A Arnaiz-Villena; M Timon; A Corell; P Perez-Aciego; J M Martin-Villa; J R Regueiro
Journal: N Engl J Med Date: 1992-08-20 Impact factor: 91.245

8. The Origin of Amerindians and the Peopling of the Americas According to HLA Genes: Admixture with Asian and Pacific People.

Authors: A Arnaiz-Villena; C Parga-Lozano; E Moreno; C Areces; D Rey; P Gomez-Prieto
Journal: Curr Genomics Date: 2010-04 Impact factor: 2.236