Literature DB >> 23959586

Pd(0)-catalyzed benzylic arylation-oxidation of 4-methylquinazolines via sp3 C-H activation under air conditions.

Dan Zhao1, Min-Xue Zhu, Yue Wang, Qi Shen, Jian-Xin Li.   

Abstract

An efficient and selective Pd(0)-catalyzed sp(3) C-H bond arylation-oxidation of 4-methylquinazolines is reported. The method enables the introduction of arylketone at the benzylic position of 4-methylquinazolines without the use of an additional directing group, and atmospheric oxygen is used as the sole oxidant.

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Year:  2013        PMID： 23959586     DOI： 10.1039/c3ob41488d

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  5 in total

1.  Tandem C(sp3)-H Arylation/Oxidation and Arylation/Allylic Substitution of Isoindolinones.

Authors:  Jacqueline Jiménez; Byeong-Seon Kim; Patrick J Walsh
Journal:  Adv Synth Catal       Date:  2016-08-02       Impact factor: 5.837

2.  Palladium-Catalyzed Benzylic C-H Arylation of Azaarylmethylamines.

Authors:  Byeong-Seon Kim; Jacqueline Jiménez; Feng Gao; Patrick J Walsh
Journal:  Org Lett       Date:  2015-11-17       Impact factor: 6.005

3.  Palladium-Catalyzed Benzylic Arylation of Pyridylmethyl Silyl Ethers: One-Pot Synthesis of Aryl(pyridyl)methanols.

Authors:  Alexandra R Rivero; Byeong-Seon Kim; Patrick J Walsh
Journal:  Org Lett       Date:  2016-03-23       Impact factor: 6.005

4.  Synthesis of triarylmethanols via tandem arylation/oxidation of diarylmethanes.

Authors:  Jianyou Mao; Kelly Eberle; Jiadi Zhang; Carles Rodriguez; Zhenfeng Xi; Miquel A Pericàs; Patrick J Walsh
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

5.  Chemoselective Palladium-Catalyzed Deprotonative Arylation/[1,2]-Wittig Rearrangement of Pyridylmethyl Ethers.

Authors:  Feng Gao; Byeong-Seon Kim; Patrick J Walsh
Journal:  Chem Sci       Date:  2015-10-27       Impact factor: 9.825
  5 in total

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