Literature DB >> 23958217

Management of primary cutaneous and metastatic melanoma.

Krista M Rubin1.   

Abstract

OBJECTIVES: To review the diagnosis, staging, and treatments (both standard and novel) for advanced melanoma and discuss the nursing role in the care of patients with melanoma. DATA SOURCES: Published research and education articles, on-line journals, recent texts, and references from pertinent articles.
CONCLUSION: Most melanomas are diagnosed at early localized stages when surgery alone can be curative. For patients diagnosed with metastatic disease, treatment options have been limited and generally considered ineffective. Recent developments in tumor genetics and a greater understanding of the role of the immune system in cancer have translated to better treatments. IMPLICATIONS FOR NURSING PRACTICE: Nurses play a key role in ensuring that patients with melanoma understand their diagnosis, treatment recommendations (including supportive care, palliative chemotherapy, immunotherapies), and participation in clinical trials.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  AJCC; clinical staging; melanoma; metastatic; pathologic staging; treatment

Mesh:

Year:  2013        PMID: 23958217     DOI: 10.1016/j.soncn.2013.06.005

Source DB:  PubMed          Journal:  Semin Oncol Nurs        ISSN: 0749-2081            Impact factor:   2.315


  5 in total

1.  Ethanol extract of Ilex hainanensis Merr. exhibits anti-melanoma activity by induction of G1/S cell-cycle arrest and apoptosis.

Authors:  Ya-Qi Zhang; Hao Yang; Wei-Dong Sun; Juan Wang; Bao-Yuan Zhang; Yan-Jun Shen; Min-Qiang Yin; Yun-Xing Liu; Chang Liu; Yun Sun
Journal:  Chin J Integr Med       Date:  2017-07-25       Impact factor: 1.978

2.  Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy.

Authors:  E Lau; J Sedy; C Sander; M A Shaw; Y Feng; M Scortegagna; G Claps; S Robinson; P Cheng; R Srivas; S Soonthornvacharin; T Ideker; M Bosenberg; R Gonzalez; W Robinson; S K Chanda; C Ware; R Dummer; D Hoon; J M Kirkwood; Z A Ronai
Journal:  Oncogene       Date:  2015-03-02       Impact factor: 9.867

3.  Primary spinal cord melanoma in thoracic spine with leptomeningeal dissemination and presenting hydrocephalus.

Authors:  Dong Hwan Jeong; Chunl Kyu Lee; Nam Kyu You; Sang Hyun Kim; Ki Hong Cho
Journal:  Brain Tumor Res Treat       Date:  2013-10-31

4.  Dacarbazine combined targeted therapy versus dacarbazine alone in patients with malignant melanoma: a meta-analysis.

Authors:  Guan Jiang; Rong-Hua Li; Chao Sun; Yan-Qun Liu; Jun-Nian Zheng
Journal:  PLoS One       Date:  2014-12-11       Impact factor: 3.240

5.  Low-diluted Phenacetinum disrupted the melanoma cancer cell migration.

Authors:  Camille Fuselier; Christine Terryn; Alexandre Berquand; Jean-Marc Crowet; Arnaud Bonnomet; Michael Molinari; Manuel Dauchez; Laurent Martiny; Christophe Schneider
Journal:  Sci Rep       Date:  2019-06-24       Impact factor: 4.379

  5 in total

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