Literature DB >> 23957254

Degenerative changes of the corticospinal tract in pediatric patients showing deteriorated motor function: A diffusion tensor tractography study.

Min Cheol Chang1, Sung Ho Jang1, Jeong Pyo Seo1, Eusil Lee2, Saeyoon Kim2, Yu Hui Won3, Su Min Son1.   

Abstract

OBJECTIVE: We attempted to demonstrate the corresponding degenerative changes of the affected corticospinal tract (CST) in pediatric patients with deteriorated motor function using diffusion tensor tractography (DTT).
METHODS: We recruited three pediatric patients (corrected age: 2, 6 and 47 months, respectively) who showed impaired motor function.
RESULTS: DTT in each patient showed interruption of the CSTs of the hemisphere contralateral to the side of motor impairment. Despite motor impairment and abnormal DTT findings, none of the three patients received rehabilitative therapy. The patients (corrected age: 9, 53 and 59 months, respectively) and their parents visited our clinic again due to deterioration of motor functions. Follow-up DTT of all evaluated patients showed significant degenerative changes in the affected CSTs in accordance with the aggravation of motor impairment.
CONCLUSION: We presented degenerative changes of the affected CSTs in pediatric patients according to the deterioration of motor function.

Entities:  

Keywords:  Cerebral palsy; corticospinal tract; degeneration; diffusion tensor; rehabilitation

Mesh:

Year:  2013        PMID: 23957254     DOI: 10.3109/17518423.2013.821538

Source DB:  PubMed          Journal:  Dev Neurorehabil        ISSN: 1751-8423            Impact factor:   2.308


  2 in total

1.  The Change of Intra-cerebral CST Location during Childhood and Adolescence; Diffusion Tensor Tractography Study.

Authors:  Yong M Kwon; Hyeok G Kwon; Jessica Rose; Su M Son
Journal:  Front Hum Neurosci       Date:  2016-12-20       Impact factor: 3.169

2.  Limb Length Discrepancy and Corticospinal Tract Disruption in Hemiplegic Cerebral Palsy.

Authors:  Hyo Sung Kim; Su Min Son
Journal:  Children (Basel)       Date:  2022-08-10
  2 in total

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