Literature DB >> 23956012

Selectively N-methylated soluble IAPP mimics as potent IAPP receptor agonists and nanomolar inhibitors of cytotoxic self-assembly of both IAPP and Aβ40.

Li-Mei Yan1, Aleksandra Velkova, Marianna Tatarek-Nossol, Gerhard Rammes, Andrei Sibaev, Erika Andreetto, Michael Kracklauer, Maria Bakou, Eleni Malideli, Burkhard Göke, Jörg Schirra, Martin Storr, Aphrodite Kapurniotu.   

Abstract

Entities:  

Keywords:  IAPP receptor agonist; islet amyloid polypeptide; protein interactions; self-assembly; β-amyloid peptide

Mesh：

Substances：

Year:  2013        PMID： 23956012     DOI： 10.1002/anie.201302840

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  22 in total

Review 1.  Amylin and its G-protein-coupled receptor: A probable pathological process and drug target for Alzheimer's disease.

Authors:  Wei Qiao Qiu
Journal:  Neuroscience       Date:  2017-05-19       Impact factor: 3.590

Review 2.  Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis.

Authors:  Jinghui Luo; Sebastian K T S Wärmländer; Astrid Gräslund; Jan Pieter Abrahams
Journal:  J Biol Chem       Date:  2016-06-20       Impact factor: 5.157

3.  Key aromatic/hydrophobic amino acids controlling a cross-amyloid peptide interaction versus amyloid self-assembly.

Authors:  Maria Bakou; Kathleen Hille; Michael Kracklauer; Anna Spanopoulou; Christina V Frost; Eleni Malideli; Li-Mei Yan; Andrea Caporale; Martin Zacharias; Aphrodite Kapurniotu
Journal:  J Biol Chem       Date:  2017-07-06       Impact factor: 5.157

4.  Effects of Amylin Against Amyloid-β-Induced Tauopathy and Synapse Loss in Primary Neurons.

Authors:  Qini Gan; Hongbo Yao; Hana Na; Heather Ballance; Qiushan Tao; Lorene Leung; Hua Tian; Haihao Zhu; Benjamin Wolozin; Wei Qiao Qiu
Journal:  J Alzheimers Dis       Date:  2019       Impact factor: 4.472

Review 5.  Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development.

Authors:  Rebekah L Bower; Debbie L Hay
Journal:  Br J Pharmacol       Date:  2016-05-18       Impact factor: 8.739

6.  Positive association between plasma amylin and cognition in a homebound elderly population.

Authors:  Wei Qiao Qiu; Rhoda Au; Haihao Zhu; Max Wallack; Elizabeth Liebson; Huajie Li; James Rosenzweig; Mkaya Mwamburi; Robert A Stern
Journal:  J Alzheimers Dis       Date:  2014       Impact factor: 4.472

7.  Rationally designed, nontoxic, nonamyloidogenic analogues of human islet amyloid polypeptide with improved solubility.

Authors:  Hui Wang; Andisheh Abedini; Bela Ruzsicska; Daniel P Raleigh
Journal:  Biochemistry       Date:  2014-09-11       Impact factor: 3.162

8.  Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease.

Authors:  H Zhu; X Wang; M Wallack; H Li; I Carreras; A Dedeoglu; J-Y Hur; H Zheng; H Li; R Fine; M Mwamburi; X Sun; N Kowall; R A Stern; W Q Qiu
Journal:  Mol Psychiatry       Date:  2014-03-11       Impact factor: 15.992

9.  General amyloid inhibitors? A critical examination of the inhibition of IAPP amyloid formation by inositol stereoisomers.

Authors:  Hui Wang; Daniel P Raleigh
Journal:  PLoS One       Date:  2014-09-26       Impact factor: 3.240

Review 10.  Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.

Authors:  Rehana Akter; Ping Cao; Harris Noor; Zachary Ridgway; Ling-Hsien Tu; Hui Wang; Amy G Wong; Xiaoxue Zhang; Andisheh Abedini; Ann Marie Schmidt; Daniel P Raleigh
Journal:  J Diabetes Res       Date:  2015-11-15       Impact factor: 4.011
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