Literature DB >> 23956

Simultaneous monitoring by optical techniques of respiratory chain and intracellular pH in toad ventricle strip.

J C LaManna, J J Saive, V W Macdonald, F F Jöbsis.   

Abstract

Intracellular pH and oxidative metabolism can be measured in toad ventricle strips simultaneously by the use of the pH indicator dye, neutral red, and a rapid scanning spectrophotometer. The effects of hypoxia and acidification on mechanical function are approximately additive. The decrease in tension due to slight acidification is probably through an effect on the portion of the twitch tension supported by anaerobic metabolism.

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Year:  1978        PMID： 23956     DOI： 10.1007/BF01944678

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Direct measurement of the intracellular pH of mammalian cardiac muscle.

Authors:  D Ellis; R C Thomas
Journal:  J Physiol       Date:  1976-11       Impact factor: 5.182

2.  Oxidation-reduction changes of cytochromes following stimulation of amphibian cardiac muscle.

Authors:  J RAMIREZ
Journal:  J Physiol       Date:  1959-06-23       Impact factor: 5.182

3.  Early changes in myocardial hypoxia: relations between mechanical function, pH and intracellular compartmental metabolites.

Authors:  F Lai; J Scheuer
Journal:  J Mol Cell Cardiol       Date:  1975-04       Impact factor: 5.000

4.  Spectrophotometric measurements of metabolically induced pH changes in frog skeletal muscle.

Authors:  V W MacDonald; J H Keizer; F F Jöbsis
Journal:  Arch Biochem Biophys       Date:  1977-12       Impact factor: 4.013

5.  Effect of pH on the kinetics of frog muscle phosphofructokinase.

Authors:  B Trivedi; W H Danforth
Journal:  J Biol Chem       Date:  1966-09-10       Impact factor: 5.157

6.  Editorial: the early "pump" failure of the ischemic heart.

Authors:  A M Katz; H H Hecht
Journal:  Am J Med       Date:  1969-10       Impact factor: 4.965

7.  Metabolic interrelations of substrates, pH, and oxygen in perfused rabbit heart.

Authors:  A F Whereat; J Nelson
Journal:  Am J Physiol       Date:  1974-06

8.  The effect of alkalosis upon the mechanical and metabolic response of the rat heart to hypoxia.

Authors:  J Scheuer; W Stezoski
Journal:  J Mol Cell Cardiol       Date:  1972-12       Impact factor: 5.000

9.  The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver.

Authors:  D H Williamson; P Lund; H A Krebs
Journal:  Biochem J       Date:  1967-05       Impact factor: 3.857

10.  Spectrophotometric studies on the pH of frog skeletal muscle. PH change during and after contractile activity.

Authors:  V W MacDonald; F F Jöbsis
Journal:  J Gen Physiol       Date:  1976-08       Impact factor: 4.086
  10 in total
  2 in total

Review 1.  Intracellular pH determination by absorption spectrophotometry of neutral red.

Authors:  J C LaManna
Journal:  Metab Brain Dis       Date:  1987-09       Impact factor: 3.584

2.  Regional changes in intracellular pH determined by neutral red histophotometry and high energy metabolites during cardiac arrest and following resuscitation in the rat.

Authors:  R C Crumrine; J C LaManna; W D Lust
Journal:  Metab Brain Dis       Date:  1991-09       Impact factor: 3.584
  2 in total

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